Slow waves represent one of the prominent EEG signatures of non-rapid eye movement (non-REM) sleep and are thought to play an important role in the cellular and network plasticity that occurs during this behavioral state. These slow waves of natural sleep are currently considered to be exclusively generated by intrinsic and synaptic mechanisms within neocortical territories, although a role for...

Burst suppression (BS) is an electroencephalogram (EEG) pattern that is characterized by brief bursts of spikes, sharp waves, or slow waves of relatively high amplitude alternating with periods of relatively flat EEG or isoelectric periods. The pattern is usually associated with coma, severe encephalopathy of various etiologies, or general anesthesia. We describe an unusual case of anoxic brain...

During much of sleep, cortical neurons undergo near-synchronous slow oscillation cycles in membrane potential, which give rise to the largest spontaneous waves observed in the normal electroencephalogram (EEG). Slow oscillations underlie characteristic features of the sleep EEG, such as slow waves and spindles. Here we show that, in sleeping subjects, slow waves and spindles can be triggered no...

IINUMA, K., NARISAWA, K., YAMAUCHI, N., YOSHIDA, T. and MIZUNO, T. Pyridoxine Dependent Convulsion: Effect of Pyridoxine Therapy on Electro encephalograms. Tohoku J. exp. Med., 1971, 105 (1), 19-26 In a 7-month old boy with vitamin B6 dependent convulsion it was found that distribution of energy % of the EEG basic waves as well as an auto-correlogram of EEG remained abnormal 24 hours after an i...

Slow waves are the most prominent electroencephalographic (EEG) feature of sleep. These waves arise from the synchronization of slow oscillations in the membrane potentials of millions of neurons. Scalp-level studies have indicated that slow waves are not instantaneous events, but rather they travel across the brain. Previous studies of EEG slow waves were limited by the poor spatial resolution...

Objectives: Autism Spectrum Disorder (ASD) is a group of neurodevelopment syndromes with impairments in social communications and restrictive or repetitive behaviors. Neurofeedback is a new method that may regulate neuro and metabolic function in brain. This study is semi-experimental, with pre and post test.  Methods: In 26 children with ASD, 40 sessions of Neurofeedback were done. Brain...

Background and aims: The aim of this study was to investigate the relationship between brain waves and Beck Depression Inventory(BDI) score in clinical cases with depression. Methods: In this study, EEG was taken using neurofeedback device at the point F4 of dorsolateral prefrontal cortex (DLPFC) of the brain of 60 depressed patients referred to psychiatr...

The most prominent EEG events in sleep are slow waves, reflecting a slow (<1 Hz) oscillation between up and down states in cortical neurons. It is unknown whether slow oscillations are synchronous across the majority or the minority of brain regions--are they a global or local phenomenon? To examine this, we recorded simultaneously scalp EEG, intracerebral EEG, and unit firing in multiple brain...

A 24-year-old male with recurrent hypersomnia associated with decreased blood flow in the thalamus on single photon emission computed tomography (SPECT) is reported. In the hypersomnolent period, the decrease of blood flow in the left thalamus was revealed in the SPECT and slow waves appeared sporadically or sometimes as a burst on the electroencephalogram (EEG). In a phase of insomnia in the c...

During non-REM sleep the EEG is dominated by slow waves which result from synchronized UP and DOWN states in the component neurons of the thalamocortical network. This review focuses on four areas of recent progress in our understanding of these events. Thus, it has now been conclusively demonstrated that the full expression of slow waves, both of natural sleep and anesthesia, requires an essen...