The medicinal plant Maytenus ilicifolia is a commonly used phytomedicine for the treatment of gastritis. The high dose required and low density of these extracts make necessary a daily intake of several capsules, hindering adherence to the medication. The purpose of this work was to develop a suitable dosage form for the administration of Maytenus ilicifolia using effervescent granules. A 23 fa...

2 List of all formulations aranged.In the present study, the design of an oral effervescent tablet of diclofenac potassium was carried out. Six different formulations were prepared using different.The objective of the present study was to formulate aspirin tablets by direct. Method using fewer excipients and to compare this formulation with the other. Study was to formulate Effervescent tablet ...

Our work is being conducted with the aim to develop an effervescent atomizer for industrial burners that will generate a fine and stable spray in large turn-down ratio. The single-hole, plain orifice atomizer is powered with light heating oil and uses air as an atomizing medium in the “outside-in” gas injection configuration. Published design concepts of the effervescent atomizer are described....

The aim of this study was to evaluate the influence of Na-bicarbonate as an effervescent agent on the floating and sustained-release characteristics in 0.1 M HCl of tablets made of Eudragit E PO (EE) and/or Eudragit L-100-55 (EL) as matrix formers at different EE:EL weight ratios: 0:100, 25:75, 50:50, 75:25, and 100:0. The tablets were made by direct compression utilizing metronidazole as a mod...

Abstract. The purpose of this research was to develop and evaluate effervescent gastric floating tablets of propranolol HCl. The oral delivery of antihypertensive propranolol HCl was facilitated by preparing an effervescent floating dosage form which could increase its absorption in the stomach by increasing the drug's gastric residence time. In the present work, effervescent floating tablets w...

Granul effervescent merupakan serbuk kasar sampai sekali mengandung unsur obat dalam campuran yang kering, biasanya terdiri dari natrium bikarbonat, asam sitrat, dan tartrat bila ditambah dengan air, basanya bereaksi membebaskan karbondioksida sehingga menghasilkan buih. Sediaan bentuk Effervescent dapat rasa enak disebabkan adanya karbonat mana membantu memperbaiki beberapa tertentu. Penelitia...

A Novel floating controlled release drug delivery system of famotidine was formulated in an effort to increase the gastric retention time of the dosage form and to control drug release. The present work investigates the approach using two different polymers HPMC K100 M and natural polymer Chitosan . A floating drug delivery system (FDDS) was developed using gas-forming agents, like sodium bicar...

BACKGROUND Oral solution N-acetylcysteine (NAC) is an antidote for acetaminophen overdose, but its unpleasant taste and aroma can impede delivery even after the coadministration of antiemetic medications. Flavored effervescent NAC tablets dissolved in water might be a more palatable formulation than oral solution NAC diluted with soft drink. OBJECTIVES To evaluate the relative bioavailability...

The Food and Drug Administration (FDA) is issuing a final rule to amend the final monograph (FM) for over-the-counter (OTC) nasal decongestant drug products (drug products used to relieve nasal congestion due to a cold, hay fever, or other upper respiratory allergies) to add phenylephrine bitartrate (PEB), both individually and in combination drug products in an effervescent dosage form, as gen...