In this paper, we report on a cost effective and simple method for fabricating a flexible multi-electrode array for subdural neural recording. The electrode was fabricated using a PDMS-Parylene bilayer to combine the major advantages of both materials. Mechanical and electrical characterizations were performed to confirm functionality of a 16-site electrode array under various flexed/bent condi...

Intracranial electrocortical recording and stimulation can provide unique knowledge about functional brain anatomy in patients undergoing brain surgery. This approach is commonly used in the treatment of medically refractory epilepsy. However, it can be very difficult to integrate the results of cortical recordings with other brain mapping modalities, particularly functional magnetic resonance ...

OBJECTIVE EEG topographies may be distorted by electrode bridges, typically caused by electrolyte spreading between adjacent electrodes. We therefore sought to determine the prevalence of electrode bridging and its potential impact on the EEG literature. METHODS Five publicly-available EEG datasets were evaluated for evidence of bridging using a new screening method that employs the temporal ...

Bio-electrodes have traditionally been made of materials such as metal and silicon that are much stiffer than the tissue from which they record or stimulate. This difference in mechanical compliance can cause incomplete or ineffective contact with the tissue. The electrode stiffness has also been hypothesized to cause chronic low-grade injury and scar-tissue encapsulation, reducing stimulation ...

spike sorting is a class of techniques used in the analysis of electrophysiological data. studying the dynamics of neural activity via electrical recording relies on the ability to detect and sort neural spikes recorded from a number of neurons by the same electrode. this article reviews methods for detecting and classifying action potentials, a problem commonly referred to as spike sorting.

OBJECTIVE Micro-electrocorticography (μECoG) offers a minimally invasive neural interface with high spatial resolution over large areas of cortex. However, electrode arrays with many contacts that are individually wired to external recording systems are cumbersome and make recordings in freely behaving rodents challenging. We report a novel high-density 60-electrode system for μECoG recording i...

29 Increasing demand exists for smaller multichannel electrodes that enable simultaneous 30 recordings of many neurons in a non-invasive manner. We report a novel method for 31 manufacturing ultra-small carbon fiber electrodes with up to 7 closely spaced recording sites. 32 The electrodes were designed to minimize damage to neuronal circuitry and to be fully 33 customizable in 3D so that their ...

Goddard, P., Keith, I., Marcovitch, H., Roberton, N. R. C., Rolfe, P., and Scopes, J. W. (1974). Archives of Disease in Childhood, 49, 853. Use of a continuously recording intravascular oxygen electrode in the newborn. The use of a continuously recording intravascular Po, electrode is described. The electrode, based on the Galvanic principle, is built into the tip of a French gauge (FG) 5 umbil...

Traditional multibarreled pipette electrodes are still widely used in microiontophoresis studies. Although better electrodes have been introduced, they are difficult and time-consuming to make. Construction of a carbon fiber recording and microiontophoresis assembly is described here. The construction of a carbon fiber electrode assembly is easy and carbon fibers have excellent characteristics ...