Combinations of antiarrhythmic drugs are frequently used to treat refractory ventricular tachycardia (VT), but few scientific data support this practice. We examined the efficacy and electrophysiology of 110 antiarrhythmic drug combination trials at electrophysiologic study in 74 patients with recurrent ventricular tachycardia. Lidocaine was combined with quinidine in 33 trials, procainamide in...

OBJECTIVE To determine the approach that pediatric electrophysiologists use as they evaluate asymptomatic patients with Wolff-Parkinson-White (WPW) syndrome regarding electrophysiologic testing and radio frequency ablation. METHODS A 21-question survey was mailed to 66 pediatric electrophysiologists who had voluntarily submitted patient data at any time to the Pediatric Radio Frequency Ablati...

BACKGROUND Accessory pathway (AP) ablation is not always easy. Our purpose was to assess the age-related prevalence of AP location, electrophysiological and prognostic data according to this location. METHODS Electrophysiologic study (EPS) was performed in 994 patients for a pre-excitation syndrome. AP location was determined on a 12 lead ECG during atrial pacing at maximal preexcitation and ...

Case presentation A 79-year-old patient with a medical history of hypertension, diabetes, ischemic heart disease, and severe aortic stenosis underwent transaortic valve implantation (TAVI) of an Edwards SAPIEN S3 26 mm valve. The tracing in Figure 1 was recorded during electrophysiologic study performed 5 days after TAVI owing to the occurrence of a Figure 1 Tracing recorded during electrophysi...

To characterize the electrophysiologic properties of the ventricular arrhythmias occurring during reperfusion after acute coronary artery ligation, a study was undertaken to correlate the time course of appearance of such arrhythmias with specific electrophysiologic mechanisms. Thirty-seven dogs survived 30minute ligations of the left descending coronary artery, and all had either instantaneous...

Electrophysiologic studies were performed on a 73-year-old man with swallowing-induced supraventricular tachycardia, in order to define the characteristics of this unique dysrhythmia in this patient. Swallowing reliably provoked an automatic atrial focus type of atrial tachycardia, which usually changed into an atrioventricular nodal reentrant tachycardia when a critical delay in atrioventricul...

Microelectrode recordings from cells in rabbit ciliary epithelium have been made in vitro. Ionophoresis of Lucifer Yellow dye from microelectrodes during measurements of potential confirmed that the recordings were intracellular. Dye passed from the impaled cells into adjacent cells in both the nonpigmented and pigmented layers of the epithelium. Electrical coupling between epithelial cells als...

We would like to express our enthusiasm with the repercussion of the article “Change in Surgical Conduct Motivated by Intraoperative Transesophageal Echocardiogram”, since the two letters published in the last issue of the journal mentioned it. Regarding the brilliant explanation on the estimated systolic blood pressure of the pulmonary artery in cases of right ventricular outlet (RVO) obstruct...

BACKGROUND Quinidine is very effective in preventing the reinduction of sustained ventricular fibrillation (VF) during electrophysiologic study (EPS) in patients with idiopathic VF and Brugada syndrome. However, there are no data on the long-term reproducibility of this EP efficacy. METHODS AND RESULTS Nine patients (seven males and two females, aged 21-72 years), who suffered from aborted ca...

Cardiac arrhythmias are common in chagasic patients. Electrophysiologic study is an invasive procedure for the investigation of sinus node function, atrioventricular node conduction and intraventricular (His-Purkinje) conduction and the mechanism of tachycardias. It is useful in elucidating syncope, dizziness and tachycardiac palpitations that remain unexplained by non-invasive diagnostic metho...