Effective cell invasion into thick electrospun biomimetic scaffolds is an unsolved problem. One possible strategy to biofabricate tissue constructs of desirable thickness and material properties without the need for cell invasion is to use thin (<2 µm) porous electrospun meshes and self-assembling (capable of tissue fusion) tissue spheroids as building blocks. Pre-stretched electrospun meshes r...

This data article contains data related to the research article entitled "3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration" by Stachewicz et al. [1]. In this paper we include additional data showing degradation analysis of poly(d,l-lactide-co-glycolide acid) (PLGA) electrospun fibers in medium and air using fiber diameter distribution histograms. W...

This research aims to investigate the possibility of electrospun fibers from Polymers of Intrinsic Microporosity (PIM-1) as an alternative adsorbent for aniline removal from both air and aqueous solution. Adsorption properties of electrospun PIM-1 fibers were compared with powder and film form of PIM-1. While electrospun PIM-1 nanofibrous mat can adsorb 871 mg g-1 aniline from air, it can also ...

Guidance of neurite extension and establishment of neural connectivity hold great importance for neural tissue regeneration and neural conduit implants. Although bioactive-epitope functionalized synthetic or natural polymeric materials have been proposed for the induction of neural regeneration, chemical modifications of these materials for neural differentiation still remain a challenge due to...

The mechanical and tribological properties of electrospun fiber mats are of paramount importance to their utility in a large number of applications. In this work, mats of electrospun fibers of poly(hexamethylene adipamide) (PA 6,6) with average fiber diameter of 238 ± 22 nm are characterized for their crystal structure as well as their mechanical and tribological properties. Post-spin thermal a...

Hydraulic permeability of electrospun fiber mats under flow-induced compression has been modeled and verified experimentally. The permeation model accurately estimates the changes in solidity, and hence the permeability of the electrospun mats, over a range of pressure differentials. The model is based on Darcy’s law applied to a compressible, porous medium, using Happel’s equation for the perm...

Ceramic nanofibers (NFs) have recently been developed for advanced applications due to their unique properties. In this article, we review developments in electrospun ceramic NFs with regard to their fabrication process, properties, and applications. We find that surface activity of electrospun ceramic NFs is improved by post pyrolysis, hydrothermal, and carbothermal processes. Also, when combi...

Silk possesses many beneficial wound healing properties, and electrospun scaffolds are especially applicable for skin applications, due to their smaller interstices and higher surface areas. However, purified silk promotes microbial growth. Selenium nanoparticles have shown excellent antibacterial properties and are a novel antimicrobial chemistry. Here, electrospun silk scaffolds were doped wi...

Electrospun membranes of polycaprolactone are widely used for biomedical applications like wound dressings and tissue engineering scaffolds. It is important to sterilize this material using the most accepted method, the gamma irradiation. In this study, we have evaluated the sterilizability of electrospun polycaprolactone membranes with gamma radiation of varying doses. The irradiated materials...

Electrospinning was used to fabricate non-woven nanofibrous tubular scaffolds from Bombyx mori silk fibroin using an all aqueous process. Cell studies and mechanical characterization tests were performed on the electrospun silk tubes to assess the viability of their usage in bioengineering small-diameter vascular grafts. Human endothelial cells and smooth muscle cells were successfully cultured...