Particles preparation from biodegradable polymers as carriers for the controlled release of drugs has been the focus of many investigations and the subject of a growing field of research in recent years. The aim of this study was to develop and optimize the preparation of oxycellulose beads containing diclofenac sodium as a model drug. Particle size, surface, drug content and encapsulation effi...

Three most commonly used preparative methods, dry-film, reverse phase evaporation and ethanol injection were employed to prepare cationic liposomes composed of DC-Chol and DOPE, respectively. The resulting samples were contrasted through morphology observation, particle size and zeta potential analysis. Sephadex filtration method with high selectivity was developed to determine the encapsulatio...

The purpose of this study was to optimize a method for the encapsulation of P5 peptide, a new designed peptide containing MHC class I epitopes from rat HER2/neu protein, into liposomes as an approach for breast cancer vaccine formulation. The efficiency of liposomal encapsulation of peptides is generally low and development of an optimized method to increase encapsulation efficiency is a big ch...

In order to improve its stability and catalytic rate in flour, the immobilization of glucose oxidase (GOX) was investigated in this work. The enzyme was encapsulated in calcium alginate-chitosan microspheres (CACM) using an emulsification-internal gelation-GOX adsorption-chitosan coating method. The interaction between alginate and chitosan was confirmed by infrared spectroscopy (IR). The resul...

the current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. among different vehicles, cationic liposomes are frequently used for delivery of genetic material. this investigation aims to prepare and optimize dotap cationic liposomes containing an antisense oligonuclotide (asodn) against protein kinase c alpha in non-small cells lung...

this study aims to investigate the capability of forming itraconazole containing niosomes with span 60 and brij 58 as non-ionic surfactants. lower cost and higher stability makes niosomes a more suitable choice in comparison with liposomes.the capability to form vesicles as an itraconazole delivery system and the influence of different factors such as type of surfactant and molar ratio of chole...

INTRODUCTION Developing strategies for the delivery of hydrophilic drugs and macro molecules such as proteins and peptides is emerging as an important in research field as several new synthesized molecules are hydrophilic in nature. Some of the major problem incurred by the small hydrophilic molecules is low encapsulation, low permeability across barriers, shorter half-life in the circulatory s...

[Abstract] In this paper, the transport efficiency of Multi Protocol Encapsulation (MPE), Unidirectional Lightweight Encapsulation (ULE) and Generic Stream Encapsulation (GSE) for typical IP packet sizes is compared. Moreover, the aggregated efficiency when applying packet-level forward error correction (PL-FEC) with MPE, ULE and GSE is also analyzed. MPE-FEC is the mechanism used by DVB-H wher...

Present study describes microencapsulation of eugenol using gelatin-sodium alginate complex coacervation. The effects of core to coat ratio and drying method on properties of the eugenol microcapsules were investigated. The eugenol microcapsules were evaluated for surface characteristics, micromeritic properties, oil loading and encapsulation efficiency. Eugenol microcapsules possessed good flo...

The objective of this study was to prepare diclofenac sodium loaded microparticles using the single emulsion [oil-in-water (o/w)] solvent evaporation method. The 2 2 experimental design methodology was using the Design-Expert ® software used to evaluate the effect of two formulation variables on the properties of the microspheres in terms of particle size, morphology, encapsulation efficiency, ...