PROGRESSIVE encephalomyelopathy with cerebellar degeneration has been described in captive cheetahs (Palmer and others 2001) and in young domestic cats (Palmer and Cavanagh 1995). This case report describes the clinical and histopathological findings in a very similar condition affecting a young snow leopard (Uncia uncia) that had been born in a zoological park in eastern England as part of the...

Recently several patients were reported in Japan, who had been noticed diarrhea or other gastrointestinal symptoms in their prodromal stage and then followed by the signs resembling myelopathy or encephalomyelopathy. It remains still unknown whether they might be any of acute myelitis, neuromyelitis optica, multiple sclerosis, funicular myelosis and myeloradiculoneuritis in old criteria, or not...

BACKGROUND Acute encephalomyelopathy occurring after an allogeneic bone marrow transplant for leukaemia is a diagnostic emergency. The diagnosis can be challenging since there is a wide set of alternative diagnoses, including opportunistic infections and relapse of the leukaemia. CASE PRESENTATION A 13-year old girl presented with a severe acute myelopathy and encephalopathy. She was in prolo...

K.H., a boy, aged 7 months 3 weeks, was admitted to King's College Hospital on April 22, 1947. Birth had been normal (birth weight 63 lb.) as also was development until six weeks before admission. The infant was vaccinated at the age of 2 months. He was breast-fed entirely for six weeks, then complementary feeding was begun. The baby's behaviour was normal until six weeks before admission when ...

Recombinants of amphotropic murine leukemia virus (A-MuLV) have found widespread use in retroviral vector systems due to their ability to efficiently and stably infect cells of several different species, including human. Previous work has shown that replication-competent recombinants containing the amphotropic env gene, encoding the major SU envelope glycoprotein that determines host tropism, i...

case presentation we report a male patient with leigh’s syndrome and a family history suggestive of unknown hypotonia and malignant hyperthermia presenting for dental rehabilitation. conclusions dexmedetomidine with remifentanil can be used with no complication in this senerio. introduction usually presenting in infancy, leigh’s syndrome is an inherited condition often manifesting with seizures...