Endocrine disrupting chemicals (EDCs) have been shown to interfere with physiological systems, i.e., adversely affecting hormone balance (endocrine system) , or disrupting normal function, in the female and male reproductive organs. Although endocrine disruption is a global concern for human health, its impact and significance and the screening strategy for detecting these synthetic or man-made...

Abstract Drinking water contains emerging contaminants, i.e., endocrine disrupting compounds (EDCs). However, the extent to which it is publicly viewed as a potential risk that requires attention (public awareness, political obligation, and regulatory efforts) substantially underrated. Thus, this study investigated drinking consumption patterns among consumers of different life stages, evaluate...

The potential effect of the so-called endocrine disruptors (EDCs) or xenoestrogens on human health and the proven effect on wildlife have got considerable attention in the scientific community. Endocrine disruption represents one of the most controversial environmental issues despite the fact that many substances, both natural and artificial, have been recognized to interfere with endocrine sig...

Endocrine disrupting compounds (EDCs) are contaminants with estrogenic or androgenic activity that negatively impact human and animal communities. These have become one of the most significant concerns for wastewater treatment in recent decades. Several studies evaluated EDC removal methods from across globe, including United Kingdom (UK). Accordingly, current study reviews municipal/domestic (...

This paper provides an introduction to a special issue dedicated to the action of environmental estrogens on neural circuits and behavior. The problem of endocrine disrupting chemicals (EDCs), i.e. chemicals that have the capacity to interfere with the endocrine system, has gained increasing attention as it has become clear that these environmental contaminants may be active in humans, as well ...

The effects of endocrine disrupting chemicals (EDCs) on reproduction are well known, whereas their developmental effects are much less characterized. However, exposure to endocrine disruptors during organogenesis may lead to deleterious and permanent problems later in life. Zebrafish (Danio rerio) transgenic lines expressing the green fluorescent protein (GFP) in specific organs and tissues are...

Endocrine disrupting chemicals (EDCs) can mimic natural hormone to interact with receptors in the endocrine system and thus disrupt the functions of the endocrine system, raising concerns on the public health. In addition to disruption of the endocrine system, some EDCs have been found associated with many diseases such as breast cancer, prostate cancer, infertility, asthma, stroke, Alzheimer's...

BACKGROUND Prostaglandins (PGs) play key roles in development and maintenance of homeostasis of the adult body. Despite these important roles, it remains unclear whether the PG pathway is a target for endocrine disruption. However, several known endocrine-disrupting compounds (EDCs) share a high degree of structural similarity with mild analgesics. OBJECTIVES AND METHODS Using cell-based tran...

Chemicals identified as endocrine-disrupting compounds (EDCs) have widespread consumer uses, yet little is known about indoor exposure. We sampled indoor air and dust in 120 homes, analyzing for 89 organic chemicals identified as EDCs. Fifty-two compounds were detected in air and 66 were detected in dust. These are the first reported measures in residential environments for over 30 of the compo...

Abstract Type 2 diabetes mellitus (T2DM), one of the most common chronic metabolic diseases, involves a complex interaction among genetic, epigenetic, and environmental risk factors. The incidence prevalence T2DM are rapidly increasing globally. In recent years, body evidences from both human animal studies have displayed an association between exposure to early unfavorable life factors such as...