introduction: antibacterial activity is one of the desirable properties of an ideal sealer. this study aimed to compare the antimicrobial effect of three different sealers, i.e. resin (ah26), calcium hydroxide (apexit) and zinc oxide eugenol (zoe) based sealers.   materials and methods: direct contact test with agar diffusion was used in this in vitro study. the freshly mixed sealers were ah26,...

(AH Plus, Endomethasone N, EndoSequence BC, MTA Fillapex and Pulp Canal Sealer EWT) using a three-dimensional (3D) cell culture model. A conventional bi-dimensional (2D) cell culture model was used as reference technique for comparison. Balb/c 3T3 fibroblasts were cultured in conventional bi-dimensional cell culture and in rat-tail collagen type I three-dimensional cell culture models. Then, bo...

With the appearance of more in vivo and ex vivo publications, methacrylate based resin sealers are becoming more popular in endodontics. Their ease of use and favorable clinical performance offer an attractive alternative to conventional endodontics. This article reviews the development of resin-based sealers and biocompatibility tests. The many, mostly opposing views are analyzed to put what h...

This in vitro study aimed to determine the susceptibility of oral specimens and ATCC lineages of Candida albicans for five endodontic sealers, which were pure and associated with two antifungal drugs, and to analyze their effect on the physical properties. For this purpose, 30 lineages of C. albicans, collected from the oral cavity of patients assisted at the endodontics clinic of the Universid...

Background and Purpose Root canal therapy is the primary method for the treatment of an infected pulp in modern dentistry. The main aim of endodontic treatment is the elimination of bacteria and their products from infected root canals. In this study, we attempted to investigate the antimicrobial activity of three root canal sealers against oral pathogens. Materials and Methods The antimicrob...

Endodontic sealers that possess both optimum flow ability and antimicrobial properties may theoretically assist in the elimination of microorganisms located in confined areas of the root canal system. The antimicrobial effects and the flow rate of the following sealers were investigated and compared: Kerr Pulp Canal Sealer EWT, Grossman's Sealer, ThermaSeal, Sealer 26, AH Plus, and Sealer Plus....

Introduction: This interventional in-vitro study aimed to evaluate the antimicrobial activity of a new Nano Zinc OxideEugenol (NZOE) sealer in comparison with AH26 and Pulpdent common root canal sealers against endodontic pathogens. Methods: The antimicrobial efficacy of three sealers(NZOE, AH26 and Pulpdent)  against Enterococcus faecalis (ATCC 29212), Escherichia coli (ATCC 25922), Streptococ...

Background. Elimination of bacteria from the root canal system is one of the aims of endodontic treatment; hence the incorporation of antibiotics into sealers can increase their antimicrobial efficacy. The aim of the present study was to determine the in vitro antimicrobial effects of AH26 and AH Plus sealers mixed with amoxicillin, triple antibiotic paste and nanosilver on Enterococcus faecali...

Introduction: Growth and proliferation of the remaining microorganisms within the root canals may destroy the surrounding tissue of the root and leads to periapical lesion. Consequently, the complete elimination of microorganisms from the root canal is a n important goal of endodontic therapy. Endodontic sealers do not provide complete seal in root canal system, and micro spaces have always rem...