We report a 14-year-old patient with recurrent pulmonary embolism due to catastrophic antiphospholipid syndrome (APS) with severe pulmonary inflammation. We considered elevated antibodies against cardiolipin and anti-beta2glycoprotein-1, but no clinical nor laboratory manifestations of systemic lupus erythematosus (SLE). Pulmonary embolism had been the first manifestation of catastrophic APS in...

BACKGROUND/AIM Enoxaparin (ENOX), the low-molecular-weight heparin, used in acute myocardial infarction (AMI) could lead to hemorrhage. The aim of this study was to determine wether bleeding was more often in AMI patients older than 65 or 75 years who receive ENOX or unfractionated heparin (UFH). METHODS Among the patients with AMI hospitalized during three successive months receiving ENOX or...

A 69 year-old female presented with bilateral amaurosis, headache, fever (38oC) and dyspnea two days after a liposuction and abdominoplasty. A bilateral papilledema was observed in the clinical examination, without other neurological changes. Her ESR was 60mm/h and her platelet count was low (55.000mm3). Brain MRI revealed restriction of diffusion sequence in the right globus pallidus and both ...

The occurrence of deep vein thrombosis during pregnancy is a rare situation with an incidence 0.6 per 1000 pregnancies. It poses diagnostic and therapeutic problem. We report case the lower limb in 19-year-old primigravida. diagnosis was suspected on basis clinical signs D-dimer assay, confirmed by venous Doppler ultrasound. Treatment consisted anticoagulation enoxaparin at dose throughout preg...

BACKGROUND Recurrent pregnancy loss is a major health problem effecting 1(see symbol) 2% of women of reproductive age. Its causes range from chromosomal abnormalities to endocrinological factors and thrombophilia related factors. Treating thrombophilias especially antiphospholipid syndrome with low dose aspirin and low molecular weight heparin improves foetal outcome. This study will add local ...

a 74-year-old male patient was admitted to our emergency department with post-mi angina. on account of the anginal complaint that continued for three days, a coronary artery angiography was undertaken. a percutaneous transluminal coronary angioplasty was performed, followed by the implantation of a coronary stent, and coronary perfusion (timi-3) was achieved in the left anterior descending arte...

OBJECTIVE Therapeutic anticoagulation is widely used, but limitations in efficacy and bleeding complications cause an ongoing search for new agents. However, with new agents developed it seems to be an inherent problem that increased efficiency is accompanied by an increase in bleeding complications. We investigate whether targeting of anticoagulants to activated platelets provides a means to o...

BACKROUND The optimal antithrombotic treatment during a primary percutaneous coronary intervention (pPCI) is not known. This single center registry study aims to assess the safety of a novel antithrombotic regimen combining enoxaparine and prasugrel at presentation, followed by bivalirudin at the catheterisation laboratory. METHODS All consecutive patients who underwent a pPCI were collected ...

A 68-year-old woman was admitted for an anterolateral myocardial infarction (MI). She had neurofibromatosis type 1 (NF-1) and 2 previous hospitalizations for non–ST-segment elevation MI, medically treated. In those episodes, aneurysmal coronary arteries with fresh thrombus in left anterior descending artery (LAD) were described. Emergent coronary angiography (CA) revealed a giant aneurysm in th...