Although polymerase chain reaction (PCR) is a highly sensitive procedure for the diagnosis of enteroviruses, it has never been systemically applied to the treatment of enteroviral encephalitis using intravenous immunoglobulin (IVIg). We conducted a 2-year randomized, controlled comparison of reverse transcription (RT)-PCR of cerebrospinal fluid (CSF) with traditional viral isolation to guide IV...

Two cases of disseminated enteroviral infection occurred in patients who received the CD20 monoclonal antibody obinutuzumab. Clinical features included hepatitis, edema, and a dermatomyositis-like syndrome. These manifestations may be unfamiliar to clinicians and are possibly responsive to intravenous immunoglobulin. Clinicians should remain vigilant for enteroviral infections in patients recei...

autoimmune diseases: an update. BMC Med. 2013;11:88 http://dx.doi. org/10.1186/1741-7015-11-88. 6. Casulo C, Maragulia J, Zelenetz AD. Incidence of hypogammaglobulinemia in patients receiving Rituximab and the use of intravenous immunoglobulin for recurrent infections. Clin Lymphoma Myeloma Leuk. 2013;13:106–11. http://dx.doi.org/ 10.1016/j.clml.2012.11.011 7. Goede V, Fischer K, Busch R, Engel...

OBJECTIVE To verify the aetiological involvement of enterovirus and identify the viral genomic sequences in Keshan disease. DESIGN Formalin fixed, paraffin embedded myocardial necropsy tissue samples were collected in Keshan disease endemic regions. Fourteen cases with a histologically confirmed diagnosis of subacute or chronic Keshan disease were studied. Control tissue included 10 samples o...

UNLABELLED Enteroviral RNA detection in myocarditis and dilated cardiomyopathy is rare. Enteroviral particles and RNA have recently been identified in patient's skeletal muscle, suggesting that skeletal more than heart muscle hosts the virus in chronic infection. Enteroviral RNA and virus-like particles were found in the myocardium and in the skeletal muscle of two patients with fatal myocardit...

PURPOSE Meningitis is among the most common infections affecting the central nervous system. It can be difficult to determine the exact pathogen responsible for the infection and patients are often treated with empiric antibiotics. This study was conducted to identify the most common clinical characteristics of enteroviral meningitis in children and evaluate the diagnostic efficacy of reverse t...

Enteroviral meningoencephalitis was diagnosed in a patient with an immunodeficiency syndrome acquired after treatment with rituximab for a relapsed primary B-cell lymphoma. A second meningoencephalitic episode was diagnosed 6 months later and was successfully treated with a combination of immunoglobulins and pleconaril. The infection was persistent since the enterovirus genome was detected in f...

Latar belakang : COVID-19 adalah penyakit pneumonia atipikal yang disebabkanSARS-CoV-2. Penyebaran dan tingkat kematian meningkat setiap harinya sertamanifestasi klinis beragam salah satunya manifestasi neurologis. Manifestasineurologis dari dapat memengaruhi baik CNS ataupun PNS dengandiagnosis seperti meningoencephalitis, kejadian cerebrovaskuler, kejang, GBS, dananosmia/ageusia (Desai,I., et...

introduction human brucellosis is a public health problem worldwide. neurobrucellosis is a rare and severe form of systemic infection and has a broad range of clinical syndromes. case presentation we reported a 21-year-old woman who was referred to our clinic with a subacute onset of fever, myalgia, and weakness of right foot, which gradually progressed and involved lower limbs and culminated i...