The erythrocytes represent an important source of antioxidant capacity of the blood. Catalase (EC 1.11.1.6.) is one of the enzymatic components of their antioxidant defense system. The objective of this study was to follow erythrocyte catalase (CAT) in 7-, 15-, 21-, 35-, 60- and 90-day-old Wistar rats of both sexes in normoxia and after exposure to intensive acute hypobaric hypoxia. During the ...

Aerobic life is connected with continuous production of free radicals, particularly reactive oxygen species (ROS). Cells posses an enzymatic and non-enzymatic antioxidant system to maintain redox homeostasis. Oxidant-antioxidant imbalance resulting in excessive accumulation of ROS is defined as oxidative stress. Oral lichen planus (OLP) is a chronic inflammation of unknown etiology. Several res...

introduction throughout their life cycle, plants are subjected to various types of environmental stresses which include salinity, water deficit, temperature extremes, toxic metal ion concentration and uv radiation. these environmental factors limit the growth and productivity of plants to various degrees, depending upon severity of stress. heavy metal toxicity is one of the major current enviro...

Although only recently Punica granatum (pomegranate) has been acclaimed for its health benefits, this fruit has long been cultivated and consumed, as a fresh fruit or in the form of beverage, especially in the Mediterranean region. In the present study, the antioxidant effects of the methanolic extract of pomegranate peels (MEPP) and pomegranate juice (PJ) were evaluated in normal male rats. Al...

It has been established that intense physical exercise is associated with an increase in free radical production. Our body has defense system to combat the deleterious effect. But, when the body’s natural defense system against free radicals are overwhelmed, oxidative stress increases. In the present investigation, we studied the effect of vitamin supplementation (composed of 400 IU of vitamin ...

Introduction. Inflammation-destructive process, accompanying cellulitis, leads to the disturbances of metabolic processes and an imbalance of the antioxidant defense system. Increased free radical generation and lipid peroxidation has been considered to play an important role in the pathogenesis of cellulitis. Salivary parameters (components) reflect the patients’ metabolic state and have clini...

Various abiotic stresses lead to the overproduction of reactive oxygen species (ROS) in plants which are highly reactive and toxic and cause damage to proteins, lipids, carbohydrates and DNA which ultimately results in oxidative stress. The ROS comprises both free radical (O(2)(-), superoxide radicals; OH, hydroxyl radical; HO(2), perhydroxy radical and RO, alkoxy radicals) and non-radical (mol...

The cells continuously produce free radicals and reactive oxygen species as a part of metabolic processes. Increased aerobic metabolism during exercise is a potential source of oxidative stress. Also, anaerobic physical activity and oxidative stress are interrelated because the intense anaerobic activity leads to damage proteins, lipids and nucleic acids in muscle cells and blood. Complex syste...

Skin cells are constantly exposed to reactive oxygen species (ROS) and oxidative stress from exogenous and endogenous sources. UV radiation is the most important environmental factor in the development of skin cancer and skin aging. The primary products caused by UV exposure are generally direct DNA oxidation or generation of free radicals which form and decompose extremely quickly but can prod...

A major cause of male infertility, which includes 50 causes of infertility, is oxidative stress.  The aerobic respiration in the sperm cell is associated with the production of reactive oxygen species (ROS). Some reactions such as sperm capacitation and acrosome reactions require moderate levels of ROS. However, when the amount of ROS production surpasses the natural antioxidant defense of the ...