effects of gibberellic acid (ga) and abscisic acid (aba) on dormant and after-ripened wheat seed, cultivar rl4137, were studied. the aim of the study was to evaluate the effects of seed after-ripening in comparison with gibberellin application on breaking of seed dormancy. moreover, the effect of abscisic acid on dormancy induction was also evaluated. acid and alkaline posphatase activity of se...

The influence of a pancreatic enzyme, lipase, on doxorubicin-loaded anionic liposomes, their complexes with spherical polycationic brushes, and ternary brushes bovine serum albumin has been studied. two-stage kinetics the enzyme-induced disturbance liposomal membrane integrity investigated using fluorescence spectroscopy. A 120-min induction period free any serious damage to liposome membranes ...

Inducible nitric oxide synthase (iNOS) gene expresses a calcium calmudolin-independent enzyme which can catalyse NO production from L-arginine. The induction of iNOS activity has been demonstrated in a wide variety of cell types under stimulation with cytokines and lipopoly saccharide (LPS). Previous studies indicated that all nitric oxide synthases (NOS) activated in human umbilical vein endot...

Characterization of the time course and magnitude of enzyme induction due to multiple inducers is important for interpretation of clinical data from drug-drug interaction studies. A population interaction model was developed to quantify efavirenz autoinduction and further induction with concurrent carbamazepine coadministration. Efavirenz concentration data in the absence and presence of carbam...

The usefulness of urinary glucaric acid determinations to measure enzyme induction by drugs was investigated by correlating its excretion rate with the daily drug regimen of 100 hospitalized patients. The urinary excretion of glucaric acid was higher in patients than in normal controls. Patients treated with enzyme inducers excreted more glucaric acid than patients not getting them, as well as ...