نتایج جستجو برای: epidemiology of retinoblastoma
تعداد نتایج: 21170815 فیلتر نتایج به سال:
Background & Aim: Retinoblastoma is the most frequent intra-ocular tumor in childhood. The tumor has both endophytic and exophytic patterns of growth. After enucleation, the pathologist is called on to evaluate risk of further growth for prophylactic therapy. Invasion of the choroid or optic nerve are risk factors for developing metastases, but occasionally, metastatic or locally invasive t...
in the retinoblastoma research, it is of great interest to identify molecular markers associated with the genetics of tumorigenesis. micrornas (mirnas) are small non-coding rna molecules that play a regulatory role in many crucial cellular pathways such as differentiation, cell cycle progression, and apoptosis. a body of evidences showed dysregulation of mirnas in tumor biology and many disease...
conclusions intra-ophthalmic artery melphalan is an effective treatment for advanced cases of retinoblastoma, with a reasonable level of success. in the short follow up period of this study, it appears that the primary cases showed better results in the control of tumor. background the management of retinoblastoma remains a challenge to the multidisciplinary team, particularly as treatment affe...
Retinoblastoma is a rare type of eye cancer that usually occurs in early childhood, usually before the age of five. This type of cancer occurs in the retina, the light-sensitive tissue behind the eye that recognizes light and color. It is the most common type of eye cancer in children. One-third of all retinoblastomas are inherited, meaning that mutations in the RB1 gene are present in all cell...
Missing evidences in cancer genetics: The retinoblastoma paradigm * Sir, Retinoblastoma (Rb) is the most common primary malignant intraocular tumour in childhood, with an incidence of 1 in 15,000 live births. It essentially affects the retina of young children under the age of five years, and may involve one eye (unilateral retinoblastoma) or both (bilateral retinoblastoma). Retinoblastoma is c...
in this issue of iranian journal of ophthalmology (irjo) han yue et al1 from china have presented a very interesting investigation on “histopathologic risk factors of retinoblastoma: a retrospective study of 104 enucleated eyes” which we are very grateful of the authors. before indicating few points about this article and their pathologic classification it is worthwhile to mention the “proceedi...
Background: Retinoblastoma is the most common embryonic tumor of retina of children. This tumor include 3-4% of all children malignancies during the age range 0-14 years. In this study, we reported the incidence, therapeutic protocols, and treatment outcome of children with RB in South west Iran. Methods: We retrospectively investigated the medical reports clinical and pathological features of...
background and objectives: retinoblastoma is the most common intraocular pediatric malignancy. angiogenic factor expression such as vegf (vascular endothelial growth factor) in retinoblastoma can be confirmatory angiogenic potential of this tumor. this study was performed to determine the role of angiogenesis in local invasion of retinoblastoma and its correlation with patients’ survival. mater...
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