A risk assessment tool for contaminated sites in low-permeability fractured media is developed, based on simple transient and steady-state analytical solutions. The discrete fracture (DF) tool, which explicitly accounts for the transport along fractures, covers different source geometries and history (including secondary sources) and can be applied to a wide range of compounds. The tool success...

We have shown previously that epimorphin (EPM), a protein expressed on the surface of myoepithelial and fibroblast cells of the mammary gland, acts as a multifunctional morphogen of mammary epithelial cells. Here, we present the molecular mechanism by which EPM mediates luminal morphogenesis. Treatment of cells with EPM to induce lumen formation greatly increases the overall expression of trans...

Our previous experiments have shown that adult male Wistar rats can differ systematically in elevated plus-maze (EPM) behaviour, which was related to the neurotransmitter serotonin in the ventral striatum. The EPM serves as a model of anxiety-like behaviour, and there is evidence that interleukin (IL)-2 in the brain may be related to anxiety-like behaviour, and that IL-2 interacts with the stri...

Trabalho realizado no Departamento de Oftalmologia da Universidade Federal de São Paulo. 1 Prof(a). Titular do Departamento de Oftalmologia UNIFESP/EPM. 2 Médica do Departamento de Oftalmologia UNIFESP/ EPM. 3 Doutor pelo Departamento de Oftalmologia UNIFESP/ EPM. 4 Profa Afiliada do Departamento de Oftalmologia UNIFESP/EPM. 5 Livre Docente e Profa Afiliada do Departamento de Oftalmologia UNIFE...

1 MD (Resident ENT Physician at EPM-UNIFESP). 2 MD, Head and Neck Surgeon (MD, Head and Neck Surgeon at EPM-UNIFESP). 3 MD, ENT, Head and Neck Surgeon (MD, ENT, Head and Neck Surgeon at EPM UNIFESP). 4 MSc on Pathology at EPM-UNIFESP (Professor in the Department of Pathology at EPM-UNIFESP). 5 Adjunct Professor in the Department of Otorhinolaryngology and Head and Neck Surgery at EPM-UNIFESP (V...

We have shown previously that epimorphin (EPM), a protein expressed on the surface of myoepithelial and fibroblast cells of the mammary gland, acts as a multifunctional morphogen of mammary epithelial cells. Here, we present the molecular mechanism by which EPM mediates luminal morphogenesis. Treatment of cells with EPM to induce lumen formation greatly increases the overall expression of trans...

Instituição: Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp), Fundação Sistema Estadual de Análise de Dados (Fundação SEADE), São Paulo, SP, Brasil 1Mestre em Pediatria pela EPM, Unifesp; Médica Assistente da Disciplina de Pediatria Neonatal da EPM, Unifesp, São Paulo, SP, Brasil 2Médica Colaboradora da Disciplina de Pediatria Neonatal da EPM, Unifesp, São Paulo, ...

Division of Child Neurology / Department of Neurology and Neurosurgery / Federal University of São Paulo, São Paulo SP, Brazil (UNIFESP-EPM): Resident, Division of Child Neurology, UNIFESP-EPM; Resident, Department of Radiology, Heliopolis Hospital, Sao Paulo SP, Brazil; Post-Graduate Researcher, Division of Child Neurology / Department of Neurology and Neurosurgery, UNIFESP-EPM; Associated Phy...