نتایج جستجو برای: erythrocytosis
تعداد نتایج: 780 فیلتر نتایج به سال:
I HE ASSOCIATION of renal neoplasms with erythrocytosis is now well known, although the mechanism by which the erythrocytosis develops remains obscure. The possibility is present that the tumor cells themselves secrete an erythropoietic principle which, by its action on the bone marrow, leads to erythrocytosis. Erythrocytosis is, at times however, associated with single or multiple renal cysts ...
The association of mutations in the PHD2 protein of the hypoxia-sensing pathway and erythrocytosis has only been established in the last decade. Here we report the case of a novel PHD2 gene mutation in a patient with erythrocytosis and summarize all reported cases to date. Case Report. A 55-year-old man presented with dyspnea and a previous diagnosis of idiopathic erythrocytosis. PHD gene seque...
cytokines or tumor-related proteins) which circulate in the bloodstream, affecting the function of other tissues at a site distant from the tumor origin. The prevalence of HCC-related paraneoplastic erythrocytosis ranges from 1% to 3%.[1,2] The underlying pathophysiology of HCCrelated paraneoplastic erythrocytosis is multifactorial. Firstly, local hypoxia from focal hepatic tumor necrosis leads...
Several etiologies have been proposed for erythrocytosis associated with uterine leiomyoma. We report a case of erythrocytosis associated with a large uterine leiomyoma, in which specific immunostaining for erythropoietin was positive. A 55-year-old woman, gravida 0, para 0, was referred to our hospital for treatment for a large uterine myoma and erythrocytosis. She had no vaginal bleeding afte...
The transcription of the erythropoietin (EPO) gene is tightly regulated by the hypoxia response pathway to maintain oxygen homeostasis. Elevations in serum EPO level may be reflected in an augmentation in the red cell mass, thereby causing erythrocytosis. Studies on erythrocytosis have provided insights into the function of the oxygen-sensing pathway and the critical proteins involved in the re...
Hemoglobin (Hb) Sherwood Forest is a rare high-affinity hemoglobin first described in 1977, arising from an Arg to Thr substitution at codon 104 of the beta chain. This hemoglobin variant has been identified in few individuals and has been associated with a compensatory erythrocytosis in the homozygous state. Prior scarce case reports have noted that heterozygotes for this variant are phenotypi...
Background: Post-transplant erythrocytosis (PTE) is characterized by persistent hematocrit level above 51% that develops in 10-20% of kidney recipients, mostly 2 years after kidney transplantation. PTE is self limited in 25% of the patients but can be persistent in other patients with an increased susceptibility for thrombosis. The purpose of this study was to identify the risk factors for deve...
Anemia is a common complication in end-stage renal disease (ESRD) patients. On the other hand, idiopathic erythrocytosis is extremely rare, with only a few cases reported in the literature. We present a case of erythrocytosis that developed after initiating hemodialysis. A 68-year-old male with a history of ESRD secondary to diabetes presented with erythrocytosis that started a few months after...
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