The purpose of this study was to investigate asymmetries in detection of horizontal motion in normal infants and children and in patients with infantile esotropia. Motion detection thresholds (% motion signal) were measured in 75 normal infants and in 36 eyes of 27 infants with infantile esotropia (ET), using a forced-choice preferential looking paradigm with random-dot patterns. Absolute motio...

Monocular oscillatory-motion visual evoked potentials (VEPs) were measured in prospective and retrospective groups of infantile esotropia patients who had been aligned surgically at different ages. A nasalward-temporal response bias that is present prior to surgery was reduced below pre-surgery levels in the prospective group. Patients in the retrospective group who had been aligned before 2 yr...

AIM This prospective study compares the results of bilateral medial rectus recession versus (vs) Y-split recession of medial recti techniques for surgical management of essential infantile esotropia. PATIENTS AND METHODS Thirty patients were included in this study and had preoperative infantile esotropia with large angles (ie, >30 prism diopters [PD]). Patients were divided into Group A, whic...

To the Editors: I read with interest the article, “Analysis of Risk Factors for Consecutive Exotropia and Review of the Literature” by Yurdakul and Ugurlu.1 The authors are to be congratulated in documenting their findings of increased risk factors for the development of consecutive exotropia such as anisometropia, amblyopia, and postoperative adduction defects. The authors reported that “no at...

Infantile esotropia is a common ophthalmic disorder in childhood. It is often accompanied by profound maldevelopment of stereopsis, motion processing, and eye movements, despite successful surgical realignment of the eyes. The proper timing of surgery has been debated for decades. There is growing evidence from clinical and animal studies that surgery during the early critical periods enhances ...

Botulinum toxin (BOTOX®) has been reported to have success as an alternative to traditional surgery for patients with infantile and early onset acquired strabismus. Selected cases with smaller angles may do well with botulinum toxin as a primary treatment; however, the large angle associated with most cases of infantile esotropia in my experience prevents its use. We report the use of botulinum...

PURPOSE To elucidate the causative factors in infantile esotropia, we evaluated morphological abnormalities in brain structures of esotropia patients showing any abnormal neurological signs in comparison to those of normal controls. METHODS Sixty-five developmentally normal children participated in this study. Of these 65, 38 demonstrated infantile esotropia and 27 were normal controls. All u...