The effect of buspirone, a drug with mainly 5-HT1A-agonist activity, on voluntary ethanol intake was tested in a rat model of alcoholism. In this model the treatment consists of an injection of ethanol (2.0 g/kg) or saline once a week, preceded by a 24 h choice between water and ethanol (10% w/v). This weekly injection of ethanol reduces voluntary ethanol intake in male rats. Maximal inhibition...

Withdrawal from an acute bolus injection of ethanol produces affective or emotional signs that include anxiogenic-like behavior and conditioned place aversion. This study assessed whether brain reward deficits that accompany withdrawal from chronic ethanol dependence are also observed upon withdrawal from acute intoxication. Rats were implanted with stimulating electrodes aimed at the medial fo...

Exotic ambrosia beetles are damaging pests in ornamental tree nurseries in North America. The species Xylosandrus crassiusculus (Motshulsky) and Xylosandrus germanus (Blandford) are especially problematic. Management of these pests relies on preventive treatments of insecticides. However, field tests of recommended materials on nursery trees have been limited because of unreliable attacks by am...

TO THE EDITOR: As ethanol is frequently used in radiopharmaceutical injections, we were interested in the effect of ethanol by injection. Several questions crossed our mind. What is the maximum concentration of ethanol that we can inject without side effects? What is the hemolytic potential of ethanol? Can we dilute ethanol-containing injections just with water? Ethanol can be used in radiophar...

In single treatment study, ethanol was administered intraperitoneally to ICR mice (about 34 g) in the amounts of 1.0, 2.0, 3.0 or 4.0 g/kg body weight. The 3,4-dihydroxyphenylacetic acid (DOPAC) + homovanillic acid (HVA) concentration in the striatum was elevated with 3.0 and 4.0 g/kg of ethanol. In the hypothalamus, the DOPAC, HVA and 5-hydroxyindoleacetic acid concentrations were increased af...

A flow injection enthalpimetric method for the determination of ethanol in fuel-grade ethanol, based on the heat of dilution of ethanol, is described. The accuracy and precision were 0.05% of ethanol; interferences by several substances are discussed. A similar procedure was also applied to the determination of ethanol in wines and spirits after distillation, yielding a precision of 0.0%0.1% of...

--This research is aimed to investigate experimentally the performance and exhaust emission characteristics of a direct injection (DI) diesel engine when fuelled with blends of conventional diesel fuel and ethanol, blends of rice bran methyl ester with ethanol, blends of diesel and rice bran methyl ester over the entire range of load on the engine. The experimental results showed that the highe...

The development of tolerance to alcohol with chronic consumption is an important criterion for an animal model of alcoholism and may be an important component of the genetic predisposition to alcoholism. The aim of this study was to determine whether the selectively bred Warsaw High Preferring (WHP) line of alcohol-preferring rats would develop behavioral and metabolic tolerance during the free...

We read with great interest the article entitled “Effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts” by Ozgen (1), which has been recently published in Diagnostic and Interventional Radiology. However, we would like to address some limitations. First, simple breast cysts do not need any follow-up, as they do not show malignant transforma...