umbilical cord blood (ucb) as a source of hematopoietic stem/progenitor cells (hspcs) used for umbilical cord blood transplantation (ucbt). the main obstacle in application of this source as an appropriate source of hspcs is low volume of this product. so ex vivo expansion of these cells in a microenvironment which mimic body condition is important. in current study we designed biocompatible mi...

Despite progress in our understanding of the growth factors that support the progressive maturation of the various cell lineages of the hematopoietic system, less is known about factors that govern the self-renewal of hematopoietic stem and progenitor cells (HSPCs), and our ability to expand human HSPC numbers ex vivo remains limited. Interest in stem cell expansion has been heightened by the i...