Active nucleocytoplasmic transport is a key mechanism underlying protein regulation in eukaryotes. While nuclear protein import can be controlled in space and time with a portfolio of optogenetic tools, protein export has not been tackled so far. Here we present a light-inducible nuclear export system (LEXY) based on a single, genetically encoded tag, which enables precise spatiotemporal contro...

This paper presents some preliminary work in the area of export control for nuclear proliferation. The long term goal is to access and analyse data that may relate to the trade of nuclear dual-use items and technologies: this data is available through various open sources. The immediate goal is to work on a table of correspondence between codes that describe, on one side, nuclear items and the ...

In this research, we investigate how knowledge in the export trading industry is created. Prior research focuses on general businesses in local market environment. This research specifically focuses on export trading with overseas market needs. These needs require attention to different types of control and requirements beyond that of a local market. In this paper, Nonaka et al.’s theory of org...

Ownership structure and industry characteristics as internal and external factors respectively significantly impact the export performance of Chinese manufacturing firms. Three different yet related models, namely, logit, tobit and ordered probit models, that correspond to three different indicators of export performance are considered. It was found that the export performance of Chinese manufa...

The Nonproliferation Review/Fall 1996 30 Dr. Bates Gill heads the Project on Security and Arms Control in East Asia at the Stockholm International Peace Research Institute. Kensuke Ebata is a member of the Japanese Security Export Control Committee and a defense and military affairs consultant in Tokyo. Matthew Stephenson is a scholar in the East Asian Studies Department at Harvard University a...

Autoregulatory loops often provide precise control of the level of expression of specific genes that encode key regulatory proteins. Here we have defined a pathway by which Yra1p, a yeast mRNA export factor, controls its own expression. We show that YRA1 exon 1 sequences in cis and Yra1p in trans inhibit YRA1 pre-mRNA splicing and commit the pre-mRNA to nuclear export. Mex67p and Crm1p jointly ...

Bacterial Tat systems export folded proteins, including FeS proteins such as NrfC and NapG, which acquire their cofactors before translocation. NrfC and NapG are proofread by the Tat pathway, and misfolded examples are degraded after interaction with the translocon. Here, we identify TatD as a crucial component of this quality control system in Escherichia coli. NrfC/NapG variants lacking FeS c...