INTRODUCTION Plasmacytoma is a monoclonal proliferation of plasma cells. It can be an isolated lesion, for which the term extramedullary plasmacytoma is used, or a representation of multiple myeloma.The upper respiratory tract is the most common site for an extramedullary plasmacytoma. Sinonasal plasmacytomas cause different symptoms depending on the sites of origins and the areas of involvemen...

extramedullary plasmacytomas are plasma cell tumors that arise outside the bone marrow. they are most often located in the head and neck. extramedullary plasmacytomas account for approximately 3 percent of plasma cell malignancies. the diagnosis of an extramedullary plasmacytoma depends upon the demonstration of a monoclonal plasma cell tumor at an extramedullary site with no evidence of multip...

INTRODUCTION The gross majority of extramedullary plasmacytomas arise in the lymphatic tissue of the upper respiratory tract. On average, one third of patients with a solid plasmacytoma will develop multiple myeloma, resulting in a worse clinical outcome. We describe a case of rapid recurrent extramedullary plasmacytomas in the background of an asymptomatic multiple myeloma. CASE PRESENTATION...

the incidence of extramedullary plasmacytoma is 5% of all plasma-cell neoplasms. The vast majority of extramedullary plasmacytomas present as a tumor secondary to systemic myelomatosis of the bone marrow; extramedullary plasmacytoma involving the pancreas is very rare, and only 19 cases have been reported in the English-language literature (1). A few such reports have described the radiologic f...

Extramedullary haematopoiesis is the production of blood elements outside the bone marrow cavity. In our case computed tomography and magnetic resonance imaging revealed the presence of a rare localization of extramedullary haematopoiesis with encasement of the biliary system in a 59 years-old male Caucasian patient, with chronic myelofibrosis and hepatic failure's symptomatology. Computed tomo...

Rationale: Gastrointestinal solitary extramedullary plasmacytoma (EMP) is rare, just occupies about 5% of all EMPs. The most common site is small intestine followed by stomach. The colorectal incidence is much rare. Patient concerns: A 63-year-old female had an episodic pain around the umbilicus for about one week. The hyperemia and edema in the ileocecal mucosa were found in colonoscopy, and t...

References APPLEBY, A., BATSON, G.A., LASSMAN, L.P. & SIMPSON, C.A. (1964) Spinal cord compression by extramedullary haematopoiesis in myelosclerosis. J. Neurol. Neurosurg. Psychiat. 27, 313. ASK-UPMARK, E. (1945) Tumour-simulating intra-thoracic heterotopia of bone marrow, Acta radiol. (Stockh.), 26, 425. BRANNAN, D. (1927) Extramedullary hematopoiesis in anaemias. Bull. Johns Hopk. Hosp. 41 1...

Extensive unilateral extramedullary hematopoiesis of the choroid was observed in an otherwise clear cut case of abusive head trauma with bilateral retinal hemorrhage, optic nerve sheath hemorrhage and peripapillary intrascleral hemorrhage. Review of 60 archival cases of suspected abusive head trauma identified two more examples of extramedullary hematopoiesis in abusive head trauma that initial...

Extramedullary myelopoiesis occurs commonly in tumor-bearing animals and is known to lead to accumulation of peripheral myeloid-derived suppressor cells (MDSC), which play an important role in immune escape. However, the cellular and molecular mechanisms by which tumors induce extramedullary myelopoiesis are poorly understood. In this study, we found that osteopontin expressed by tumor cells en...

INTRODUCTION Extramedullary hematopoiesis occurs in approximately 15% of cases of thalassemia. Intracranial deposits of extramedullary hematopoiesis are an extremely rare compensatory process in intermediate and severe thalassemia. CASE PRESENTATION We present an unusual case of an intracranial extramedullary hematopoiesis with a choroid plexus origin in a 34-year-old Caucasian man with beta ...