Tetracycline may be used to treat several types of bacterial diseases in ruminants. In addition, tetracycline is added to food to promote the growth. There are few reports on the pharmacokinetics of tetracycline in sheep. Therefore, the objective of this study was to examine the pharmacokinetic characteristics of the drug in sheep. Ten apparently healthy mixed-breed sheep were administered 20 m...

MicroRNAs (miRNAs) are endogenous, noncoding RNAs that regulate various biological processes including adipogenesis and fat metabolism. Here, we adopted a deep sequencing approach to determine the identity and abundance of miRNAs involved in fat deposition in adipose tissues from fat-tailed (Kazakhstan sheep, KS) and thin-tailed (Tibetan sheep, TS) sheep breeds. By comparing HiSeq data of these...

This blinded, randomised experimental study was designed to compare the analgesic effects of lumbosacral epidural administration of lidocaine-epinephrine or lidocaine-xylazine combinations in fat-tailed sheep. Nine healthy fat-tailed male lambs (mean ± s.d. age, 4.6 ± 0.4 months; weight, 24.6 kg ± 2.5 kg) were randomly allocated into four groups of six sheep: lidocaine 2% (LID), lidocaine-e...

tetracycline may be used to treat several types of bacterial diseases in ruminants. in addition, tetracycline is added to food to promote the growth. there are few reports on the pharmacokinetics of tetracycline in sheep. therefore, the objective of this study was to examine the pharmacokinetic characteristics of the drug in sheep. ten apparently healthy mixed-breed sheep were administered 20 m...

Endocarditis is rarely reported in sheep and information presented for ovine endocarditis is based mostly on comparative findings in the cattle. Infective vegetative endocarditis of the right heart was diagnosed in a 3-year-old fat-tailed ram. Clinical findings included tachycardia, marked brisket edema, jugular veins distention and pulsation and pale mucous membranes. Hematologic abnormality i...

The melanocortin receptor 1 (MC1R) plays a central role in regulation of animal coat color formation. In this study, we sequenced the complete coding region and parts of the 5'- and 3'-untranslated regions of the MC1R gene in Chinese sheep with completely white (Large-tailed Han sheep), black (Minxian Black-fur sheep), and brown coat colors (Kazakh Fat-Rumped sheep). The results showed five sin...

This blinded, randomized experimental study was designed to evaluate the analgesic effects of adding epinephrine or xylazine to lidocaine solution for brachial plexus block (BPB) in sheep. Nine healthy, fat-tailed female lambs (26.6 ± 1.5 kg) were randomly allocated into three groups: lidocaine 2%, 5 mg kg-1 (LID, n = 6), lidocaine (5 mg kg-1) with epinephrine 5 µg mL...

endocarditis is rarely reported in sheep and information presented for ovine endocarditis is based mostly on comparative findings in the cattle. infective vegetative endocarditis of the right heart was diagnosed in a 3-year-old fat-tailed ram. clinical findings included tachycardia, marked brisket edema, jugular veins distention and pulsation and pale mucous membranes. hematologic abnormality i...

BACKGROUND: Fat-tailed sheep breeds have a  unique  ability  to  tolerate  periods  of  negative  energy  balance  due to seasonal changes in feed availability. This ability is attributed to presence  of  fat-tail  as  a  body  energy  reserve, however the exact underlying  mechanisms  controlling  the  response  of adipose  tissue  depots  to variations in energy balance in fat-tailed breeds a...