Precise knowledge of mutation rate at Y-STRs loci is essential for a correct evaluation of typing results in forensic casework and specially kinship genetic studies. In this study, we have examined 252 confirmed and unrelated father/son sample pairs from Moroccan population using the 17 Y-STR markers DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a, DYS385b, DYS437, DYS438, DYS...

Significant intrafamilial correlations of left ventricular mass exist in first-degree relatives. However, the specific maternal and paternal influences on left ventricular mass of offspring remain unknown. We therefore evaluated familial aggregation of left ventricular mass by type of familial relation in two European populations. A random sample of 159 nuclear families (250 parents and 321 off...

Empirical evidence suggests that parents who have themselves inherited from their own parents are more likely to leave an estate to their children even after controlling for income, wealth and education. This implies an indirect reciprocal behavior between three generations by transmitting the attitude towards bequeathing from one generation to the next. We incorporate such an intergenerational...

A father and son presented ten years apart with a fourth ventricle ependymoma. The history, imaging and pathology are presented and the aetiology of familial ependymoma discussed.

Reiter's syndrome consists of a non-specific urethritis, conjunctivitis, polyarthritis, and a number of less constant features (Reiter, 1916). The cause of the urethritis is unknown but it is commonly regarded by venereologists as an infective condition of venereal origin. Although a yearly average of more than 12,000 cases of non-specific urethritis have been reported to the Ministry of Health...

Six families are described in which 10 sons were involved incestuously with a natural father (N=4) or step-father (N=2). Father-son incest as a part of the spectrum of child abuse appears to be a more frequent clinical entity than was thought previously.

OF THE DISSERTATION Sins of the Father: An Investigation into Judgments and Processes Involved in Within-family Tainting by Stephanie Allison Peak Doctor of Philosophy in Psychological and Brain Sciences Washington University in St. Louis, 2017 Professor Alan J. Lambert, Chairperson The present research focused on a real-world event (i.e., the 2015 Paris terrorist attacks) as a basis for gainin...

In type I familial amyloid polyneuropathy (FAP) caused by a variant Met30-transthyretin (TTR), genetic anticipation has been reported. To determine whether anticipation of the disease is a true biological phenomenon or the result of ascertainment bias, we compared age at onset of the affected child with that of the affected parent in 68 parent-child pairs (including data on assumed age at onset...

In this report we have tried to explain the reasons behind the difference in the pattern of transfusion requirement between two members of a family with similar β-globin mutation. The father and younger son both are HbE-β, but the father never had transfusion, whereas the younger son takes transfusion monthly. Mother and the elder son are HbEE without any history of transfusion. β-globin mutati...