Thrombin generation and fibrinogen (Fbg) clotting are the ultimate proteolytic reactions in the blood coagulation pathway. Staphylocoagulase (SC), a protein secreted by the human pathogen Staphylococcus aureus, activates prothrombin (ProT) without proteolysis. The SC.(pro)thrombin complex recognizes Fbg as a specific substrate, converting it directly into fibrin. The crystal structure of a full...

In conventional ultrasound detection in structures, a fiber Bragg grating (FBG) is glued on or embedded in the structure. However, application of strain to the structure can influence the sensitivity of the FBG toward ultrasound and can prevent its effective detection. An FBG can work as a strain-insensitive ultrasound sensor when it is not directly glued to the monitored structure, but is inst...

Fiber Bragg grating(FBG) sensors, one of the fiber optic sensors(FOS), based on the wavelength division multiplexing(WDM) technology are ideally suitable for structural health monitoring of composite materials and structures. Proper monitoring of measurands in FBG sensor systems requires accurate measurement of the Bragg center wavelength, and the ability to track rapid shifts of the wavelength...

A restoration method for reflection spectra in a serial FBG sensor array with spectral shadowing is proposed and experimentally demonstrated in a WDM/TDM combined multiplexing system. The SNR of each FBG sensor is formulated and analyzed as a function of the number and reflectivities of serial FBG sensors. The maximum number of FBG sensors in a single fiber line can be determined by the approxi...

BACKGROUND New diagnostic criteria for diabetes based on fasting blood glucose (FBG) level were approved by the American Diabetes Association. The impact of using FBG only has not been evaluated thoroughly. The fasting and the 2-hour glucose (2h-BG) criteria were compared with regard to the prediction of mortality. METHODS Existing baseline data on glucose level at fasting and 2 hours after a...

BACKGROUND AND AIM Previous studies have demonstrated reduced exercise capacity in patients with diabetes mellitus. This study evaluated the relationship between fasting blood glucose (FBG) levels and exercise capacity in patients with coronary artery disease (CAD). METHODS We evaluated 986 consecutive patients with CAD referred for bicycle spiroergometry combined with gated myocardial perfus...

Thrombin (Ila)-cleavage of fibrinogen (FBG) t o form polymerized fibrin promotes ndothelial cell spreading, proliferation, and von Willebrand factor release, requiring the exposure of the p15-42 domain. Studies reported here indicate that Ilacleavage of fibrinopeptide B enhances exposure of a heparin binding domain at the /315-42 neo-N-terminus of fibrin. Crossed immunoelectrophoresis showed he...

BACKGROUND Body mass index (BMI), resting energy expenditure (REE) and fasting blood glucose (FBG) are major preoperative assessments of patients' nutrition and metabolic state. The relations and effects of these indices on esophageal cancer patients' postoperative short-term and long-term outcomes remain controversial and unclear. We aimed to study the impact of BMI, REE and FBG in esophageal ...

We theoretically and experimentally demonstrate a fiber-optic ultrasonic sensor system based on a fiber-ring laser whose cavity consisting of a regular fiber Bragg grating (FBG) and a tunable optical band-pass filter (TOBPF). The FBG is the sensing element and the TOBPF is used to set the lasing wavelength at a point on the spectral slope of the FBG. The ultrasonic signal is detected by the var...

Posttransplantation diabetes (PTD) contributes to cardiovascular disease and graft loss in renal transplant recipients (RTR). Current recommendations advise fasting blood glucose (FBG) as the screening and diagnostic test of choice for PTD. This study sought to determine (1) the predictive power of FBG with respect to 2-h blood glucose (2HBG) and (2) the prevalence of PTD using FBG and 2HBG com...