Chronic alcohol consumption perturbs the normal intestinal microbial communities (dysbiosis). To investigate the relationship between alcohol-mediated dysbiosis and pulmonary host defense we developed a fecal adoptive transfer model, which allows us to investigate the impact of alcohol-induced gut dysbiosis on host immune response to an infectious challenge at a distal organ, independent of pre...

CONTEXT Due to maldigestion, pancreatic exocrine insufficiency (PEI) in chronic pancreatitis may lead to deficiencies in fat-soluble vitamins, including vitamin D. This may, in turn, can cause disturbances in bone metabolism and reduce bone mineral density. OBJECTIVE To conduct a prospective study of maldigestion, bone metabolism, and bone mineral density in a group of patients with chronic p...

Enteric dysbiosis plays an essential role in the pathogenesis of alcoholic liver disease (ALD). Detailed characterization of the alterations in the gut microbiome is needed for understanding their pathogenic role in ALD and developing effective therapeutic approaches using probiotic supplementation. Mice were fed liquid Lieber-DeCarli diet without or with alcohol (5% v/v) for 6 weeks. A subset ...

To define the effects of moderate alcohol intake on cholesterol and triglyceride metabolism in man, twelve patients were hospitalized on a metabolic ward and were fed defined diets for 10 weeks. Each patient underwent testing of plasma lipid and lipoprotein levels, of cholesterol metabolism (absorption, fecal excretion, bile saturation), and of triglyceride metabolism [turnover of triglycerides...

A study was designed to compare the effectiveness and time efficiency of three collection-preservation methods individually and grouped to form systems. Employees and members of their families of an agricultural grower in Hillsborough County, Fla., provided all fecal specimens used in the study. The 160 individuals participating were members of 64 families and represented a cross section of all...

For the past century, public health officials have relied on fecal coliforms to identify and track bacterial contamination. However, several issues arise when using coliforms as indicators for viral pathogen risk. First, there is a lack of association between fecal coliforms and human enteric viruses in the environment. Second, there are differences in the fate of coliforms compared to viral pa...

Water quality information is important for guiding water safety management and preventing water-related diseases. To assess the current status of regulated water quality monitoring in sub-Saharan Africa, we evaluated testing programs for fecal contamination in 72 institutions (water suppliers and public health agencies) across 10 countries. Data were collected through written surveys, in-person...

PURPOSE To develop an alcoholic extract of the inner bark of the Schinus terebinthifolius raddi and to test its impact on autogenously fecal peritonitis in Wistar rats. METHODS The inner bark of the Schinus terebinthifolius raddi was kept for seven days in 70% ethanol alcohol. The total elimination of the solvent was performed in a rotary evaporator under reduced pressure at 55-60°C. Four mil...

Auto-brewery syndrome (ABS), also called gut fermentation syndrome, is an extremely infrequent but underrecognized disorder where ethanol produced endogenously, similar to a typical bioreactor. The reliability of forensic alcohol analysis results frequently challenged as the concentration in breath, blood, and/or urine constitutes important evidence for prosecuting drivers under influence alcoh...