In this clinical study, for the first time we used the direct gene therapy to restore severe injuries of the suspensory ligament branch and superficial digital flexor tendon in horses (Equus caballus). We injected the plasmid DNA encoding two therapeutic species-specific growth factors: vascular endothelial growth factor 164 and fibroblast growth factor 2 at the site of injury in the suspensory...

BACKGROUND Tendon injuries are one of the most common injuries of the hand and challenging problems in trauma surgery. They usually require surgical repair and unlike the single tendon injuries, flexor tendon injuries have higher morbidities when accompanied with nerve injuries. In the present study, I aimed to report the clinical experiences and outcomes about tendon injuries. METHODS ...

BACKGROUND The aim of the present study was to evaluate usefulness of ultrasonography in assessment of rabbit common calcanean tendon, to describe its ultrasonographic anatomy and to perform morphometric analysis of this structure. MATERIALS AND METHODS Fifteen skeletally-matured New Zealand rabbits were used in the study. Ultrasonographic examinations of common calcanean tendon (CCT) were pe...

Spontaneous rupture at the distal part of the gastrocnemius tendon (GT) is the second most common non-traumatic tendon injury in dogs, whereas the other strands of the common calcaneal tendon do not seem to have a predisposition to rupture. In order to discover why we investigated the common calcaneal tendons of 63 dogs microscopically and biomechanically. Both the gastrocnemius and superficial...

The purpose of this study was to compare sonographic and tenoscopic findings with the purpose of establishing the accuracy and limitations of ultrasonograophy as a non-invasive diagnostic modality in evaluating the DFTS and its enclosed tendons. The medical records from 22 horses which underwent tenoscopic desmotomy of the palmar/plantar annular ligament were evaluated in a retrospective study....

Although the predominant function of all tendons is to transfer force from muscle to bone and position the limbs, some tendons additionally function as energy stores, reducing the energetic cost of locomotion. To maximise energy storage and return, energy-storing tendons need to be more extensible and elastic than tendons with a purely positional function. These properties are conferred in part...

This case report describes the intralesional application of autologous conditioned plasma (ACP) in seven horses as treatment of severe tendinitis of the superficial digital flexor tendon, deep digital flexor tendon, or desmitis of the inferior check ligament. Follow-up data of the horses revealed a positive outcome in 10 to 13 months post injury. All horses treated with ACP were either performi...

Palmar ganglion is rare. Deep palmar ganglion usually arises from the wrist joint and may cause compression neuropathy. Superficial palmar ganglion may arise from the flexor tendons of the wrist. The chance of compression neuropathy is expected to be less than deep palmar ganglion. However, there is a higher chance of perforation through the skin and the ganglion may affect hand grip. Open rese...

Image texture analysis techniques have been applied for evaluating tendon injuries in racehorses. Ultrasound images from superficial and deep digital flexor tendons have been characterized and a measure for quantifying injury grade has been proposed. Wavelet-based texture segmentation and classification algorithms have been developed for quantification of the injury grades. Discrete wavelet pac...

The aim of this study was to characterize stem and progenitor cell populations from the equine superficial digital flexor tendon, an energy-storing tendon with similarities to the human Achilles tendon, which is frequently injured. Using published methods for the isolation of tendon-derived stem/progenitor cells by low-density plating we found that isolated cells possessed clonogenicity but wer...