ABST RACT Trueperella pyogenes (formerly Arcanobacterium pyogenes) is a commensal bacterium present on the upper respiratory and urogenital tract mucosa of domestic and wild animals. It is also the most common opportunistic pathogen and isolated from the infections of cattle such as mastitis, metritis, arthritis and pneumonia. The aim of this study was to determine virulence genes (plo, nanH, n...

In this work we discover that a specific recognition of the N-terminal lectin domain of FimH adhesin by the usher FimD is essential for the biogenesis of type 1 pili in Escherichia coli. These filamentous organelles are assembled by the chaperone-usher pathway, in which binary complexes between fimbrial subunits and the periplasmic chaperone FimC are recognized by the outer membrane protein Fim...

Type 1 fimbriae are one of the most important factors of Escherichia coli adaptation to different niches in the host. Our study indicated that the genetic marker--fimH gene occurred commonly in commensal E. coli derived from healthy humans but expression of the type 1 fimbriae was not observed. Identification of fim structural subunit genes (fimA-fimH) and recombinase fimE and fimB genes showed...

Filamentous type 1 pili are responsible for attachment of uropathogenic Escherichia coli strains to host cells. They consist of a linear tip fibrillum and a helical rod formed by up to 3000 copies of the main structural pilus subunit FimA. The subunits in the pilus interact via donor strand complementation, where the incomplete, immunoglobulin-like fold of each subunit is complemented by an N-t...

Bordetella avium causes an upper respiratory tract disease (bordetellosis) in avian species. Commercially raised turkeys are particularly susceptible. Like other pathogenic members of the genus Bordetella (B. pertussis and B. bronchiseptica) that infect mammals, B. avium binds preferentially to ciliated tracheal epithelial cells and produces similar signs of disease. These similarities prompted...

The purpose of this study was to determine the presence of virulence genes, perform typing for the characterization of Arcanobacterium pyogenes field strains, and investigate the correlation between clonal types, virulence genes and occurence of disease. The isolates (n=51) used in this study were isolated from different sources (liver (n=4) of sheep; liver (n=25), lungs (n=5), broncho-alveolar...

In this paper the use of Fuzzy Relational Models (FRMs) for model-based process control is investigated. The work presented here is centred around the development of a Fuzzy Internal Model Controller (FIMC) for a simulated multi-variable pH process. The paper begins with a brief introduction which sets the scene for the work. There then follows a description of the pH process and the particular...