Wilson's Disease (WD) is a rare, autosomal, recessive, inborn error of the copper metabolism, which is caused by a mutation in the copper-transporting gene, ATP7B. The presentation is usually neurologic or hepatic, which is seen in 40% of the patients. The diagnosis depends primarily on the clinical features, the biochemical parameters and the presence of the Kayser - Fleischer ring. Here, we a...

Fleischer and Mannel (FM) have shown that it may become possible to constrain the angle γ of the unitarity triangle from measurements of various B → πK decays. This constraint is independent of hadronic uncertainties to the few percent level. We show that, within the Standard Model, the FM bound gives strong constraints on the CKM parameters. In particular, it could predict a well defined sign ...

We study the online page replication problem. We present a new randomized algorithm for rings which is 2.37297-competitive, improving the best previous result of 3.16395. We also show that no randomized algorithm is better than 1.75037-competitive on the ring. This is the rst non-trivial lower bound for the problem. We initiate the study of replication in continuous metric spaces (the Nomads' P...

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we present a 19-year-old patient with hematologic and neurologic manifestations associated with wilson’s disease. idiopathic thrombocytopenia was diagnosed in october 2009. bone marrow aspiration was normal. gradually her neurologic and psychiatric symptoms emerged, dysarthria, writing apraxia, learning difficulties, emotionalism and eventually dystonia of hands. the serum ceruloplasmin was low...