the purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. polyethylene oxide (peo) and hydroxypropyl methylcellulose (hpmc) were evaluated for matrix-forming properties. a simplex lattice design was applied to systemically optimize the drug release profile. the amounts of peo wsr 303, hpmc k15m and sodium bicarbonate were selected as independen...

After a few weeks, underwater components of offshore structures are colonized by marine species and after years this growth can be significant. It has been shown that it affects the hydrodynamic loading cylinder such as legs braces for jackets, risers mooring lines floating units. Over decade, development Floating Offshore Wind Turbines highlighted specific effects due to smaller size their com...

Both lighterand hydrophobic heavier-than-liquid particles will float on liquid–air surfaces. Capillary forces cause the particles to cluster in typical situations identified here. This kind of clustering causes particles to segregate into islands and bands of high concentrations in thin liquid films rimming the inside of a slowly rotating cylinder partially filled with liquid. A second regime o...

This paper presents the characteristics of heave motion responses and hydrodynamic forces a horizontal floating circular cylinder during wave–current interaction. A two-dimensional numerical model based on CFD (Computational Fluid Dynamics) method for modeling wave flow is validated verified. The were calculated analyzed under conditions different k values (stiffness spring), amplitudes, submer...

Abstract Parametric excitation in the pitch/roll degrees of freedom (DoFs) can induce dynamic instability floating cylinder-type structures such as spar buoys, offshore wind or wave energy converters. At certain frequency and amplitude ranges input waves, parametric coupling between heave DoFs results undesirable large rotational motion. One possible remedy to mitigate existence resonance is us...