Both colonoscopy and FOBT are options for CRC screening. For those at an average risk of developing CRC, screening should start at age 50 years. The 2 screening options most often selected are colonoscopy every 10 years and annual FOBT. While FOBT is noninvasive, if a positive result is found, then a colonoscopy is recommended. Over the course of multiple years of screening, false-positive FOBT...

BACKGROUND Timely follow-up of fecal occult blood screening with colonoscopy is essential for achieving colorectal cancer mortality reduction. This study evaluates the effectiveness of two ongoing interventions designed to improve colonoscopy uptake after a positive fecal occult blood test (FOBT) result within Ontario's population-wide ColonCancerCheck program. The first was a revision of maile...

BACKGROUND Colorectal cancer screening (CRCS) reduces morbidity and mortality; however, the positive benefits might be partially offset by long-term distress following positive screening results. We examined relationships among colorectal cancer-specific worry and situational anxiety after positive fecal occult blood tests [FOBT (+)] compared with receipt of negative results. METHODS Of note,...

OBJECTIVE To determine whether medication interventions enhance the sensitivity and specificity of guaiac-based fecal occult blood testing (FOBT) when screening for colorectal cancer (CRC). DATA SOURCES We searched PubMed-MEDLINE, CINAHL, and the Cochrane databases using the MeSH headings occult blood, feces/analysis, and guaiac/analysis, linking them to variations of anticoagulants, heparin,...

BACKGROUND A comparative effectiveness intervention by this team improved initial fecal occult blood testing (FOBT) rates from 3% to 53% among community clinic patients. The purpose of this study was to evaluate the effectiveness and costs associated with a literacy-informed intervention on repeat FOBT testing. METHODS Between 2008 and 2011, a three-arm quasi-experiential comparative effectiv...

We examined prevalence and correlates of fecal occult blood testing (FOBT) uptake in a sample of men and women aged 50 to 70 years without a personal history of cancer (n=15,810). The data was collected in 2004 through the Health Care Access Panel (HCAP), a nationally generalizable survey of German households. A pronounced gender difference in FOBT use emerged. Women reported regular use more o...

AIMS AND BACKGROUND The best screening strategy for colorectal cancer is still debated. We simulated two screening strategies, namely flexible sigmoidoscopy (single episode) and immunological fecal occult blood test (FOBT) (five biennial rounds) and comparing their results as regards advanced adenomas and colorectal cancer detection. METHODS A Markov model was developed to estimate the number...

BACKGROUND To explain why rates of colorectal cancer (CRC) screening including fecal occult blood testing (FOBT), flexible sigmoidoscopy (FS), colonoscopy (CS), and barium enema (BE), are low, this study assessed determinants of CRC screening from medical records. METHODS Data were abstracted from patients aged > or =64 years selected from each clinician from 30 diverse primary care practices...

BACKGROUND Guaiac-based faecal occult blood tests (g-FOBTs) are most commonly used in colorectal cancer (CRC) screening programmes. Faecal immunochemical tests (FITs) are thought to be superior. AIM To compare performance of a g-FOBT and a quantitative FIT for detection of CRCs and advanced adenomas in a colonoscopy-controlled population. METHODS We assessed sensitivity and specificity of b...

OBJECTIVES To estimate the effectiveness, cost-effectiveness and resource impact of faecal occult blood testing (FOBT) and flexible sigmoidoscopy (FSIG) screening options for colorectal cancer to inform the Department of Health's policy on bowel cancer screening in England. METHODS We developed a state transition model to simulate the life experience of a cohort of individuals without polyps ...