The article covers the results of pathomorphological studies broiler chickens' liver (Cobb 500 cross) spontaneously damaged by Group I fowl adenovirus. Clinical signs disease in chickens appeared on 15th day life and were manifested a sharp decrease water feed consumption. was lethargic for several days, breathing hard, mostly sitting with its head down eyes closed. During breeding period, mort...

A recent outbreak of hepatitis-hydropericardium syndrome caused by serotype 4 fowl adenovirus (FAdV-4) has resulted in significant economic losses to the poultry industry worldwide. However, little is known about the molecular pathogenesis of FAdV-4. In this study, a novel monoclonal antibody (mAb) targeting the fiber-2 protein of FAdV-4 was generated, mAb 3C2. Indirect immunofluorescence assay...

The world's most numerous bird, the domestic chicken, and their wild ancestor, the red junglefowl, have long been used as model species for animal behaviour research. Recently, this research has advanced our understanding of the social behaviour, personality, and cognition of fowl, and demonstrated their sophisticated behaviour and cognitive skills. Here, we overview some of this research, star...

Outbreaks of hepatitis-hydropericardium syndrome (HHS) caused by fowl adenovirus serotype 4 (FAdV-4) and inclusion body hepatitis (IBH) related to FAdV-8b FAdV-11 have been increased in chickens China since 2015. Clinical concurrent infections FAdV-4, FAdV-8b, are quite common, yet there no commercially available trivalent vaccines against infection these three serotypes. In our previous study,...

A major impediment to the use of adenovirus as a gene therapy vector and for vaccine applications is the host immune response to adenovirus hexon-the major protein component of the icosahedral capsid. A solution may lie in novel vectors with modified or chimeric hexons designed to evade the immune response. To facilitate this approach, we have distinguished the portion of hexon that all serotyp...

Inclusion body hepatitis (IBH) is a devastating disease of chickens caused by Fowl adenovirus (FAdV) and molecular studies hexon gene important for classification FAdV isolates, epidemiology IBH infection development effective control strategy. The objective the study was to molecularly characterize isolates obtained from field outbreaks in broiler chicken 2017 2019. Liver gizzard samples named...

This study investigated an adenovirus infection in two consecutive breeding flocks the same poultry hall. Thirty-six thousand one-day-old chickens of ROSS 308 hybrid broiler type were kept together one The first flock during fattening did not show any clinical signs disease or increased mortality. Typical seen second flock. included: depression, apathy, somnolence, a crouched position with droo...