Fractional exhaled nitric oxide concentration (FENO) depends on exhalation flow; however, children often are unable to perform controlled flow procedures. Therefore, a device was developed for off-line FENO sampling, with dynamic flow restriction (DFR). The authors compared off-line with on-line FENO, assessed feasibility, and obtained normal values for FENO in children aged 4-8 yrs. Subjects i...

BACKGROUND Exhaled nitric oxide has been proposed as a marker for airway inflammation in asthma. The aim of this study was to compare exhaled nitric oxide levels with inflammatory cells and mediators in bronchoalveolar lavage fluid from asthmatic and normal children. METHODS Children were recruited from elective surgical lists and a non-bronchoscopic bronchoalveolar lavage (BAL) was performed...

INTRODUCTION Fractional exhaled nitric oxide (FeNO) is considered as a useful, noninvasive marker of airway inflammation in asthma and allergic rhinitis. It has also been suggested that anti-inflammatory treatment guided by monitoring of exhaled NO could improve overall asthma control. However, long-term intra-subject variability of this parameter as well as the rate of its change, which can be...

The primary aim of this study was to assess whether Fractional Exhaled Nitric Oxide (FeNO) and Nasal Nitric Oxide (nNO) can be used as a mean of diagnosis in Allergic Rhinitis (AR) without asthma or not , and discuss their correlation. Fifteen healthy children and thirty children with AR, but without asthma, were enrolled. A questionnaire about clinical features of AR children had been complete...

BACKGROUND Fractional exhaled nitric oxide (FeNO) is a non-invasive biomarker of airway inflammation and nitrosative stress. Previous studies have suggested a possible role of FeNO in the management of patients with pulmonary sarcoidosis, but published data are discordant. OBJECTIVES To assess the clinical usefulness of FeNO and alveolar concentration of NO (CalvNO) in sarcoidosis. METHODS ...

BACKGROUND Mylar balloons are used to collect exhaled air for analysis of fractional nitric oxide concentration (FENO). AIM We studied the effect of storage conditions on the stability of nitric oxide (NO) in mylar balloons. METHODS Exhaled air samples and calibration gases were stored in mylar balloons at 4, 21 and 37 degrees C, with or without silica gel. NO was measured after 0, 6, 9, 24...