BACKGROUND Metabolic Syndrome (MetS) is a complex disorder defined as a cluster of interconnected risk factors such as hypertension, dyslipidemia, obesity and high blood glucose levels. Premorbid metabolic syndrome (PMetS) is defined by excluding patients with previously diagnosed cardiovascular disease or diabetes mellitus from those suffering MetS. We aimed to determine the prevalence of PMet...

Disease progression is often complex and seemingly unpredictable. Moreover, patients often respond in dramatically different ways to various treatments, and determining the appropriate intervention for a patient can sometimes be difficult. In this paper, we describe an interactive visualization-based system for intervention analysis and apply it to patients at risk of developing congestive hear...

Patients: 364 patients > 18 years of age (median age 75 to 76 y, 64% men) who were hospitalized for symptomatic chronic HF (Framingham criteria and European Society of Cardiology diagnostic guidelines) and had an immediate prerandomization plasma NT-proBNP level > 50 pmol/L (about 400 pg/mL). Exclusion criteria were active myocarditis or pericarditis; severe hepatic or pulmonary disease (FEV1 <...

M e t h o d s Design: Cohort study with mean 5.2-year follow-up (Framingham Offspring Study). Setting: Community-based study in the United States. Patients: 3346 participants (mean age 58 y, 53% women) of the Framingham Off-spring Study. Exclusion criteria were HF, serum creatinine > 177 μmol/L (> 2.0 mg/dL), unavailable natriuretic peptide levels, or missing covariate or follow-up data. Risk f...

Methods We conducted a cross-sectional non-interventional study on CHC patients evaluated in a tertiary hospital in Bucharest between December 2012-August 2013. We measured fasting serum lipids, glucose, liver transaminases, inflammatory proteins, and viral load. We calculated body-mass index (BMI) and waist-to-hip ratio (WTH). Cardiovascular risk was assessed with Framingham risk score, metabo...

BACKGROUND The high burden and rising incidence of cardiovascular disease (CVD) in resource constrained countries necessitates implementation of robust and pragmatic primary and secondary prevention strategies. Many current CVD management guidelines recommend absolute cardiovascular (CV) risk assessment as a clinically sound guide to preventive and treatment strategies. Development of non-labor...

We examined the relationship in a large-living population between the concentration of triglycerides in plasma from fasting persons and the concentration of very-low-density lipoprotein cholesterol (VLDL-C) as determined after preparative ultracentrifugation. Data from individuals in the Framingham Heart Study who were free of coronary heart disease, did not have Fredrickson Type I, III, or V h...