Background: Obesity and insulin resistance refer to a clustering of various medical conditions, with a number of pathological components that contribute to the development of diabetes and cardiovascular disease. Some studies have shown that free testosterone levels are low in obese men and are inversely correlated with the degree of obesity. In addition, leptin levels increases with obesity tha...

BACKGROUND Testosterone in Older Men with Mobility Limitations Trial found an increased incidence of cardiovascular events in men randomized to testosterone, resulting in enrollment cessation by trial's Data and Safety Monitoring Board. We evaluated changes in gonadal hormones and markers of inflammation and coagulation to elucidate risk factors associated with cardiovascular events. METHODS ...

We conducted a community-based cross-sectional study to evaluate the role of genetics in determining the individual difference in total testosterone and sex hormone-binding globulin levels. Study participants comprised 730 Korean men consisting of 142 pairs of monozygotic twins, 191 pairs of siblings, and 259 father-offspring pairs from 270 families who participated in the Healthy Twin study. S...

Objective: The objective of this retrospective and cross sectional study was to assess the correlation of aging and body mass index (BMI) with hormones from hypothalamic-pituitary-gonadal (HPG) in patients with and without diabetes mellitus (DM). Research Design and Methods: Electronic medical records of 605 patients were selected using specific exclusion criteria. The subjects were systematica...

background: polycystic ovary syndrome (pcos) is the most common cause of hyperandrogenism in women. non-classic congenital adrenal hyperplasia (ncah) is very close to pcos. the diagnosis of hyperandrogenism is not based on the finding of decreased or increased levels of a single hormone. objective: in our paper, we are going to test correlation between clinical signs and biochemical markers of ...

the effects of exposure to chemical weapons containing sulfur mustards on the serum levels of total and free testosterone. gonadotropins and prolactin was investigated in young iranian men. in the first five weeks after injury both serum total and free testosterone were significantly decreased as compared to control values. three of 13 men had total testosterone below 300 ng/dl and two of six h...

The effects of exposure to chemical weapons containing sulfur mustards on the serum levels of total and free testosterone. gonadotropins and prolactin was investigated in young Iranian men. In the first five weeks after injury both serum total and free testosterone were significantly decreased as compared to control values. Three of 13 men had total testosterone below 300 ng/dL and two of ...

BACKGROUND There have been few studies examining the associations between menstrual irregularity, androgens and bone mass in population-based samples of premenopausal women. This study aimed to describe the associations between menstrual pattern, testosterone, sex hormone binding globulin (SHBG) and bone mass in a population-based sample of premenopausal women. METHODS Cross-sectional study (...

This study investigated the association between depressive symptoms in elderly Chinese men and the total testosterone, dehydroepiandrosterone (DHEA), DHEA sulphate (DHEAS), oestradiol and sex hormone-binding globulin (SHBG) levels, and the free androgen index. Cross-sectional data from 1147 community-dwelling elderly men, aged 65 and older, were used. Depressive symptoms were measured using the...