A father and his two sons each presented with atrial tachycardia in the newborn period. The father went on to develop dilated cardiomyopathy. The first son (who also had transposition of the great arteries) died from the arrhythmia after surgery. The second son is currently successfully managed pharmacologically.

In this report we have tried to explain the reasons behind the difference in the pattern of transfusion requirement between two members of a family with similar β-globin mutation. The father and younger son both are HbE-β, but the father never had transfusion, whereas the younger son takes transfusion monthly. Mother and the elder son are HbEE without any history of transfusion. β-globin mutati...

Ten (10) sets of siblings or parent-child pairs concordant for gender identity disorder (transsexualism) or gender identity disorder and transvestitism are reported. For concordant gender identity disorder, there is one set of male monozygotic twins; three sets of non-twin brothers; one brother-and-sister pair; one set of sisters; and one father and son. With gender identity disorder and transv...

Empirical evidence suggests that parents who have themselves inherited from their own parents are more likely to leave an estate to their children even after controlling for income, wealth and education. This implies an indirect reciprocal behavior between three generations by transmitting the attitude towards bequeathing from one generation to the next. We incorporate such an intergenerational...

A father and son presented ten years apart with a fourth ventricle ependymoma. The history, imaging and pathology are presented and the aetiology of familial ependymoma discussed.

Reiter's syndrome consists of a non-specific urethritis, conjunctivitis, polyarthritis, and a number of less constant features (Reiter, 1916). The cause of the urethritis is unknown but it is commonly regarded by venereologists as an infective condition of venereal origin. Although a yearly average of more than 12,000 cases of non-specific urethritis have been reported to the Ministry of Health...

THE DISCOVERY by ANGT+” and PERRIS’ that manic-depressive illness (MDI) is genetically different from unipolar depression has led to renewed interest in the genetic predisposition to to MDI. WINOKUR~-5 and his collaborators proposed a sex-linked dominant (SLD) mode of of inheritance, on the basis of familial transmission patterns in 61 pedigrees and on the basis of apparent linkage with X-chrom...