In order to reduce the chance of multiple pregnancy during in-vitro fertilisation (IVF)– embryo transfer treatment, there is an increasing trend towards transferring a lower number of embryos. Surplus good-quality embryos are then transferred in frozen-thawed embryo transfer (FET) cycles. The first pregnancy after FET was reported in 1983.1 It has been estimated that in IVF programmes in which ...

BACKGROUND Polycystic ovary syndrome (PCOS) patients are at increased risk of pregnancy complications, which may impair pregnancy outcome. Transfer of fresh embryos after superovulation may lead to abnormal implantation and placentation and further increase risk for pregnancy loss and complications. Some preliminary data suggest that elective embryo cryopreservation followed by frozen-thawed em...

Purpose The aim of the present prospective study was to investigate the efficacy of hyaluronan (HA) using two different concentrations as embryo transfer media for in vitro fertilization embryo transfer cycles. Methods A total of 169 cycles undergoing fresh embryo transfer on day 2 or 3, 561 cycles undergoing frozen-thawed embryo transfer on day 2 or 3, and 484 cycles of frozen-thawed blastoc...

OBJECTIVE To compare the effectiveness of elective single embryo transfer versus double embryo transfer on the outcomes of live birth, multiple live birth, miscarriage, preterm birth, term singleton birth, and low birth weight after fresh embryo transfer, and on the outcomes of cumulative live birth and multiple live birth after fresh and frozen embryo transfers. DESIGN One stage meta-analysi...

BACKGROUND Embryo culture media used for IVF treatment might affect fetal growth and thus birthweight of the newborns. METHODS A retrospective study was conducted in South China using data from 2370 singleton neonates born after IVF/ICSI between 2009 and 2012. Two culture media, i.e., either Vitrolife or SAGE were used as embryo culture media during the study period. Neonates' birthweights we...

The implantation of embryo depends on the quality of the embryo and the receptivity of the endometrium. While the factors affecting embryo quality were optimized, the implantation rates did not reach the desirable levels. This directs the blaming for endometrial receptivity which already has been affected by supra-physiological levels of hormone, namely estradiol, in controlled ovarian hypersti...

BACKGROUND Embryo transfer to a developed endometrium is an important prognostic factor in frozen-thawed embryo transfer cycle outcome. Vaginal estrogen, such as Vagifem vaginal tablets and Premarin vaginal cream, is a regimen used for the patients with refractive endometria. OBJECTIVE Our objective was to compare the effects of Vagifem and Premarin on the endometrial thickness of the patient...

OBJECTIVE To compare pregnancy rates with fresh and frozen embryo transfer in patients admitted to Royal Jubilee Maternity Service (RJMS), Belfast between January 1st 2004 and December 31st 2005 with ovarian hyperstimulation syndrome (OHSS). METHOD A retrospective analysis of all ART cycles (2,283) carried out in RJMS between January 1st 2004 and December 31st 2005 and of all patients admitte...

Our purpose is to explore whether anti-dsDNA antibody, which was demonstrated to enter living cells and induced apoptosis, could adversely affect reproductive outcomes. A total of 259 women receiving the in vitro fertilization-embryo transfer (IVF) cycle were enrolled in this study, including 52 women with positive ANA and anti-dsDNA (ANA+/anti-dsDNA+ group), 86 women with positive ANA and nega...

EFFICACY OF INTRAUTERINE INSTILLATION AUTOLOGOUS PLATELET-RICH PLASMA ON ENDOMETRIAL GROWTH DURING THE FROZEN-THAWED EMBRYO TRANSFER CYCLES