The stem anatomy and pollen morphology of Iranian members of the genus Corydalis (except C. seisumsiana in pollen morphology) were studied using light and SEM microscopy. The results verified the argument that the tuberous sections of Corydalis, including Radix-cava, Corydalisand Leonticoides could be classified in a single subgenus as a natural grouping. The study also revealed that the specie...

Variation of leaf morphology in Papaveraceae s.l. (including Fumariaceae and Pteridophyllum) has previously been shown to be related to developmental differences in the direction of segmentation and in blade-petiole differentiation. Based on ontogenetic comparisons, we here distinguish polyternate, acropetal, basipetal-pedate, basipetal-pinnate, and divergent modes of dissection. In addition, u...

The chemical constituents and biological activities of Corydalis crispa (Fumariaceae) were investigated for the first time. The phytochemical study resulted in the isolation of nine known isoquinoline alkaloids: protopine (1), 13-oxoprotopine (2), 13-oxocryptopine (3), stylopine (4), coreximine (5), rheagenine (6), ochrobirine (7), sibiricine (8) and bicuculline (9), with complete NMR data for ...

In our ongoing study focused on Corydalis cava (Fumariaceae), used in folk medicine in the treatment of memory dysfunctions, we have investigated fifteen previously isolated alkaloids for their potential multifunctional activity on Alzheimer's disease (AD) targets. Determination of ß-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibition was carried out using a BACE1-Immobilized En...

We report the antibacterial activity of the plant extracts and three previously isolates known compounds viz., nonacosane-10-ol (alcohol), 23a-homostigmast-5-en-3ß-ol (homolog of β-sterol) and cisand trans-prtopinium (alkaloid) of Fumaria parviflora Lam (Fumariaceae) for the first time. Plant extracts and pure compounds were in vitro assessed against seven clinical Gram (-) and Gram (+) bacteri...