The composition of essential oils and their mixtures used to formulate gin is usually too complex to separate all sample components by standard capillary gas chromatography (GC). In particular, minor constituents that possess important organoleptic properties can be masked by co-elution with major sample components. A solution is provided that combines gas chromatography/mass spectrometry (GC/M...

The review describes on-line derivatization/degradation methods employed in mass spectrometry to solve some structural and analytical problems. Advantages and applications of various positions of reaction systems connected mainly to a mass spectrometer or a gas chromatograph/mass spectrometer are considered. Among these are reaction systems connected directly to the mass spectrometer (reaction ...

Since the latter half of the 20th century mass spectrometry (MS) applications, associated with gas chromatography (GC) separation (i.e. GC-MS), have been the “gold standard” in specialised clinical laboratories for the quantitation of drugs, organic acids and steroids [1]. This status quo remained unchallenged until just over a decade ago when liquid chromatography coupled with tandem mass spec...

Acetylation with acetic anhydride, under both aqueous and anhydrous conditions, has been utilized to derivatize various biogenic amines and psychotropic drugs for subsequent analysis by gas chromatography (GC) or gas chromatography-mass spectrometry (GC-MS). Under basic aqueous conditions, acetic anhydride derivatizes phenols and amines but not alcohols; under anhydrous conditions, all three fu...

different solvent extracts of a red algae, hypnea flagelliformis,and two brown algae, cystoseira myrica and sargassum boveanum, collected from the persian gulf coast were subjected to different bioassays including: 1,1-diphenyl-2-picrylhydrazyl (dpph) free radical scavenging assay, antibacterial and antifungal activity by thin layer chromatography (tlc)-bioautography, agar disc diffusion (add) ...

Mass spectrometry has long been used in clinical laboratories. The first important applications were the use of gas chromatography–mass spectrometry (GC-MS) for drug screening and the diagnosis of organic acid metabolic disorders. More recently liquid chromatography–mass spectrometry [LC-MS; liquid chromatography–tandem mass spectrometry (LC-MS/MS)] has been introduced successfully into clinica...

Various volatile organic compounds (VOCs) in breath exhaled by patients with lung cancer, healthy controls, and patients with lung cancer who underwent surgery for resection of cancer were analyzed by gas condenser-equipped gas chromatography-mass spectrometry (GC/MS) for development of an exhaled breath monitoring prototype system involving metal oxide gas sensors, a gas condenser, and gas chr...

A quantitative analysis of the individual compounds in tobacco essential oils is performed by comprehensive two-dimensional gas chromatography (GC x GC) combined with flame ionization detector (FID). A time-of-flight mass spectrometer (TOF/MS) was coupled to GC x GC for the identification of the resolved peaks. The response of a flame ionization detector to different compound classes was calibr...

Relative to other metabolomics analysis techniques, gas chromatography mass spectrometry (GC/MS) is one of the earliest applied analysis techniques in metabolomics. The first paper on metabolomics (metabolic profiling) is derived from the application of GC/MS analysis in urine and tissue extracts (Dalgliesh et al. 1966). With the arrival of omics era and the proposing of metabolomics concept, p...