drug delivery across the skin is used for several millennia to ease gastrointestinal (gi) ailments in traditional persian medicine (tpm). tpm topical remedies are generally being applied on the stomach, lower abdomen, lower back and liver to alleviate gi illnesses such as dyspepsia, gastritis, gi ulcers, inflammatory bowel disease, intestinal worms and infections. the aim of the present study i...

(UC) is characterized by long-standing mucosal inflammation of the large bowel, with increased tendency of developing colorectal cancer (CRC), i.e., colitis-associated cancer (CAC) [1]. The other two predisposing conditions for CRC are familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC), whose genetic etiology is well defined [1]. The genetic predispositio...

The bacterial colonisation is established immediately after birth, through direct contact with maternal microbiota, and may be influenced during lactation. There is emerging evidence indicating that quantitative and qualitative changes on gut microbiota contribute to alterations in the mucosal activation of the immune system, leading to intra- or extra-intestinal diseases. A balance between pat...

The prevalence of obesity in the Japanese population has been increasing dramatically in step with the Westernization of lifestyles and food ways. Our study demonstrated significant associations between obesity and a number of gastrointestinal disorders in a large sample population in Japan. We demonstrated that reflux esophagitis and hiatal hernia were strongly related to obesity (BMI > 25) in...

background: gastrointestinal and liver diseases (gilds) are major causes of death and disability in middle east and north africa (mena). however, they have different patterns in countries with various geographical, cultural, and socio-economic status. we aimed to compare the burden of gilds in iran with its neighboring countries using the results of the global burden of disease (gbd) study in 2...

  Abstract Introduction: Gastrointestinal diseases are one of the most common and chronic non-communicable diseases that impose high stress and cost on society and the health system. Objective: The present study aimed at comparing cognitive flexibility and its dimensions between gastrointestinal patients and healthy subjects. Materials and Methods: This is a comparative analytical study. Th...