نتایج جستجو برای: gdc composite
تعداد نتایج: 122413 فیلتر نتایج به سال:
With the aim of promoting the Ni/Ce0.8Gd0.2O2-δ (Ni/GDC20) cermet anodic performance of low temperature solid oxide fuel cell (LT-SOFC) [1], nanostructuring platinum nanoparticles on NiO/GDC composite was done by single-step wet-infiltration of hexachloroplatinic acid hexahydrate (H2PtCl6.6H2O) precursor on NiO/GDC20 composite. The anodic polarization resistance was measured using symmetr...
In plants, the glycine decarboxylase complex (GDC) cooperates with serine hydroxymethyltransferase (SHMT) to mediate photorespiratory glycine-serine interconversion. GDC is also postulated to be an integral component of one-carbon (C1) metabolism in heterotrophic tissues, although molecular evidence in plants is scarce. An initial report of a xylem-specific isoform of GDC component H-protein, P...
Clinical PI3K inhibition has been somewhat disappointing, due to both inadequate patient stratification and compensatory cell signalling through bypass mechanisms. As such, investigation of PI3K-MEK co-targeted inhibition has been recommended. With high mortality rates and a clear need for new therapeutic intervention strategies, non-small cell lung cancer (NSCLC) is an important setting to inv...
Gastric duplication cyst (GDC) in an adult can have several clinical presentations. A review of the literature showed previously reported cases of GDC presenting as pancreatic pseudocyst or with greatly raised concentrations of carbohydrate antigen 19-9 (CA 19-9). It is often difficult to discriminate GDC from pancreatic cystic tumour, in particular pancreatic mucinous cystadenoma, in which con...
PURPOSE We calculated the incremental cost-utility ratio for Guglielmi detachable coil (GDC) embolization versus no therapy for unruptured intracranial aneurysms considered inappropriate for surgical clipping procedures. METHODS Decision tree and Markov analyses that employ cohort simulation were applied to determine the incremental cost-utility ratio of GDC embolization versus no therapy for...
BACKGROUND AND PURPOSE Matrix coils have been developed to prevent aneurysm recanalization. Midterm anatomic results in a prospective multicenter consecutive series including patients treated with GDC or Matrix coils for ruptured aneurysms are presented. MATERIALS AND METHODS Five hundred seventeen patients harboring ruptured aneurysms were treated with GDC (276 patients) or Matrix coils (241...
Tape casting is a well-established method for manufacturing thin ceramic layers with controllable thickness and porosity. This study investigates the potential of 10Sc1CeSZ material electrolyte anode intermediate-temperature solid oxide fuel cells (IT-SOFC) in an anode-supported cell (ASC) geometry. In order to use La0.6Sr0.4Co0.2Fe0.8 Oxide (LSCF) cathode material, Gd0.2Ce0.8 (GDC) barrier lay...
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. Limited treatment options have only marginally impacted patient survival over the past decades. The phophatidylinositol 3-kinase (PI3K) pathway, frequently altered in GBM, represents a potential target for the treatment of this glioma. 5-(6,6-Dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[4,3-e]purin-2-yl)pyrimid...
PURPOSE In a phase I trial for patients with refractory solid tumors, hedgehog pathway inhibitor vismodegib (GDC-0449) showed little decline in plasma concentrations over 7 days after a single oral dose and nonlinearity with respect to dose and time after single and multiple dosing. We studied the role of GDC-0449 binding to plasma protein alpha-1-acid glycoprotein (AAG) to better understand th...
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