A series of fluorinated macrocyclic complexes, M-DOTAm-F12, where M is LaIII, EuIII, GdIII, TbIII, DyIII, HoIII, ErIII, TmIII, YbIII, and FeII, was synthesized, and their potential as fluorine magnetic resonance imaging (MRI) contrast agents was evaluated. The high water solubility of these complexes and the presence of a single fluorine NMR signal, two necessary parameters for in vivo MRI, are...

New dinuclear MII-LnIII complexes of general formulas [Cu(µ-L)(µ-OAc)Ln(NO3)2]·CH3CN·H2O (LnIII = Gd (1), Tb (2), Dy (3) and Er (4)), [Ni(CH3CN)(µ-L)(µ-OAc)Ln(NO3)2]·CH3CN Nd (5), (6), (7), (8), (9) Y (10)) [Co(CH3CN)(µ-L)(µ-OAc)Ln(NO3)2]·CH3CN (11), (12), (13), (14) (15)) were prepared from the compartmental ligand N,N?-dimethyl-N,N?-bis(2-hydroxy-3-formyl-5-bromo-benzyl)ethylenediamine (H2L)....

We report the synthesis and characterization of trinuclear 4d-4f compounds [Co(C5Me5)2][(C5Me5)2Ln(μ-S)2Mo(μ-S)2Ln(C5Me5)2], 1-Ln (Ln = Y, Gd, Tb, Dy), containing highly polarizable MoS43- bridging unit. UV-Vis-NIR diffuse reflectance spectra DFT calculations reveal a low-energy metal-to-metal charge transfer transition assigned to from singly occupied 4dz2 orbital MoV empty 5d orbitals lanthan...

The use of GdIII complexes as contrast agents in magnetic resonance imaging (MRI) has proven invaluable in the diagnosis of several internal abnormalities.1 The range of medical applications for which contrast agents are useful is likely to increase in the future with the development of target-specific contrast agents of increased relaxivity, such as MS-325 which binds with HSA in the blood poo...