abstract  introduction: intracerebroventricular (icv) injection of streptozotocin (stz) causes cognitive impairment in rats. the beneficial effect of genistein (gen) was investigated on icv stz-induced learning, memory, and cognitive impairment in male rats. methods: for this purpose, rats were injected with icv stz bilaterally, on days 1 and 3 (3 mg/kg). the stz-injected rats received gen (1 m...

Amino acid composition and isoflavone are alleged contributors to the beneficial effects of soy protein isolate (SPI) on lipid metabolism. Therefore, we investigated the contributing component(s) of SPI in a maternal diet to the regulation of lipid metabolism in offspring. We also determined serum parameters in dams to investigate specific maternal cues that might be responsible for this regula...

We attempted to identify the Mycobacterium avium complex (MAC) isolated in Japan by using DNA probes specific for M. avium or Mycobacterium intracellulare (Gen-Probe Rapid Diagnostic System for MAC; Gen-Probe, Inc., San Diego, Calif.). The source and drug susceptibility distributions were examined. This assay system proved to be rapid, sensitive, specific, and reliable for identification of MAC...

The isoflavone genistein (GEN), a biologically active component of soy foods, is associated with reduced breast cancer risk in women who consume soy-rich diets. GEN has been reported to influence many biological processes, of which suppression of cell proliferation and stimulation of apoptosis are considered to be the major pathways underlying its inhibition of tumorigenesis. This study evaluat...

BACKGROUND Lacewings (insect order Neuroptera), known in the fossil record since the Early Permian, were most diverse in the Mesozoic. A dramatic variety of forms ranged in that time from large butterfly-like Kalligrammatidae to minute two-winged Dipteromantispidae. PRINCIPAL FINDINGS We describe the intriguing new neuropteran family Parakseneuridae fam. nov. with three new genera and 15 new ...

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this study aimed to evaluate the cellular toxicity of two newly-released acrylic resins (futura gen and gc reline hard) in comparison with the conventional heat-cure resin (meliodent).sample discs from each acrylic resin were placed in 24-well culture plates along with l929 mouse fibroblast cell line. a mixture of the rpmi 1640 medium, antibiotics and 10% fbs was added to the plates and the spe...

Eight new genera of the subfamily Limosininae are described from the Afrotropical region: Afrolimosina gen. n. (type species A. albitarsis sp. n.), Biphallapodema gen. n. (type species B. polydentata sp. n., additional species B. oligodentata sp. n.), Chelilimosina gen. n. (type species Ch. baloghi sp. n.), Mislocatus gen. n. (type species Ceroptera ealensis Vanschuytbroeck, 1951), Oligochaetos...

Genistein (GEN), one of the soy isoflavones, exhibits protection against colon cancer. The WNT signaling pathway plays a critical role in both normal epithelial regeneration and tumorigenesis in human colon. In this study it was hypothesized that GEN regulates specific genes in the WNT signaling pathway. Colon cancer cell lines DLD-1, SW480, and SW1116 were treated with Novasoy or GEN for 4 day...

X-ray mammography, the current gold standard for breast cancer detection, has a 20% false-negative rate (cancer is undetected) and increases in younger women with denser breast tissue. Diffuse optical imaging (DOI) is a safe (nonionizing), and relatively inexpensive method for noninvasive imaging of breast cancer in human subjects (including dense breast tissues) by providing physiological info...