background: numerous studies used microarray gene expression data to extract metastasis-driving gene signatures for the prediction of breast cancer relapse. however, the accuracy and generality of the previously introduced biomarkers are not acceptable for reliable usage in independent datasets. this inadequacy is attributed to ignoring gene interactions by simple feature selection methods, due...

staphylococcus aureus carrying pvl gene remain major health problem associated with highly virulent infections. characterization of such gene is important to know the impact and the functional significance of nucleotide variations. pcr and standard sequencing were performed for twelve sudanese strains from different sources. protein structures prediction, modeling and physiochemical analysis we...

Staphylococcus aureus carrying PVL gene remain major health problem associated with highly virulent infections. Characterization of such gene is important to know the impact and the functional significance of nucleotide variations. PCR and standard sequencing were performed for twelve Sudanese strains from different sources. Protein structures prediction, modeling and physiochemical analysis we...

Introduction: The advent of large-scale genome sequencing has revolutionized the field of genetics and biology. Sequencing projects require sophisticated computational analysis to manage vast collections of data. Scientists first sequenced a genome in 1977, that of a small bacteriophage consisting of 11 genes over 5.4kb of DNA. In the bacteriophage, coding genes comprise 95% of the genome. 1 Si...