Generalized estimating equations (GEE) are commonly employed for the analysis of correlated data. However, the quadratic inference function (QIF) method is increasing in popularity because of its multiple theoretical advantages over GEE. We base our focus on the fact that the QIF method is more efficient than GEE when the working covariance structure for the data is misspecified. It has been sh...

Modeling individual heterogeneity in capture probabilities has been one of the most challenging tasks in capture-recapture studies. Heterogeneity in capture probabilities can be modeled as a function of individual covariates, but correlation structure among capture occasions should be taking into account. A proposed generalized estimating equations (GEE) and generalized linear mixed modeling (G...

In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: AMS 2000 subject classification: 46N30 Keywords: B-spline Efficiency Empirical likelihood Generalized estimating equations G...

HIV (Human Immunodeficiency Virus) researchers are often concerned with the correlation between HIV viral load measurements and CD4+ lymphocyte counts. Due to the lower limits of detection (LOD) of the available assays, HIV viral load measurements are subject to left-censoring. Motivated by these considerations, the maximum likelihood (ML) method under normality assumptions was recently propose...

Vinod (1997, 1998) discuss the Godambe-Durbin theory of estimating functions (EFs) and its potential in econometrics. Here we consider a popular application of EFs called generalized estimating equations (GEE). It is typically applied to panel data, where the heteroscedasticity is analytically related to , the regression parameter, and where the dependent variable is binary. Geddes (1997) studi...

In this paper, we develop robust estimation for the mean and covariance jointly for the regression model of longitudinal data within the framework of generalized estimating equations (GEE). The proposed approach integrates the robust method and joint mean–covariance regression modeling. Robust generalized estimating equations using bounded scores and leverage-based weights are employed for the ...

background: oral health education for the mothers of very young children is important in reducing the risk of early childhood caries. this study aimed to evaluate the impact of an oral health intervention among mothers of 1-2 years old children. methods: this cluster randomized controlled trial (2012) was conducted among ninety mothers of 1-2 year old children. the setting of study was 10 child...

Researchers are often interested in analyzing data that arise from a longitudinal or clustered design. Although there are a variety of standard likelihood-based approaches to analysis when the outcome variables are approximately multivariate normal, models for discrete-type outcomes generally require a different approach. Liang and Zeger formalized an approach to this problem using generalized ...

Correlated binary data are common in biomedical studies. Such data can be analyzed using Liang and Zeger's generalized estimating equations (GEE) approach. An attractive point of the GEE approach is that one can use a misspecified working correlation matrix, such as the working independence model (i.e., the identity matrix), and draw (asymptotically) valid statistical inference by using the so-...

Surveys often contain qualitative variables for which respondents may select any number of the outcome categories. For instance, for the question "What type of contraception have you used?" with possible responses (oral, condom, lubricated condom, spermicide, and diaphragm), respondents would be instructed to select as many of the outcomes that apply. This situation is known as multiple respons...