INTRODUCTION Use of hormonal contraceptives for birth control is commonplace in the Western World. In Europe, there is considerable variety in the frequency of use of hormonal contraceptives and in the age at which these contraceptives are initiated. The purpose of the present study was to describe the use of hormonal contraceptives among the Danish adolescent female population, focusing on age...

Exogenous hormones are used by more than a hundred million women worldwide as oral contraceptives or for postmenopausal hormone replacement. Oral contraceptives increase the risk of venous thrombosis, of myocardial infarction, and of stroke. The risk is highest during the first year of use. The venous thrombotic risk of oral contraceptives is high among women with coagulation abnormalities and ...

introduction: the pilgrimage to ka’beh (god’s house in mecca) is a special opportunity in the life of most muslims. female pilgrims try to postpone menstruation during the pilgrimage by taking hormonal medicines. however, women are seen in this disorder. this paper aimed to determine the frequency of menstrual disorders and related factors among female pilgrims of umrah mufradah in 2012.methods...

Four epidemiologic studies showed a twofold increase in risk of deep venous thrombosis with the use of oral contraceptives containing third-generation progestins, relative to second-generation products. These findings have been strongly debated ever since, and new studies have been added. In the current article we examine whether the findings can be explained by potential biases or other shortc...

Third generation oral contraceptives (OC), containing the progestins desogestrel and gestodene, were introduced in the 1980s in a attempt to lower the risk of cardiovascular side effects. However, the observation that desogestrel and gestodene in combined OC were related to a 50 to 100% greater risk of venous thromboembolism (VTE) suggested that the issue is more complex than originally thought...

BACKGROUND Only 10% of plasma TFPIα (TFPI) exists in the full length form, the rest circulates as a C-terminally truncated form. However, blood platelets exclusively contain full length TFPI, which is released at the site of injury upon platelet activation, and which could play an important local regulatory role in thrombin generation and prevention of thrombosis. METHODS The anticoagulant ac...

OBJECTIVES To determine the association between myocardial infarction and use of different types of oral contraception in young women. DESIGN Community based case-control study. Data from interviews and general practice records. SETTING England, Scotland, and Wales. PARTICIPANTS Cases (n=448) were recruited from women aged between 16 and 44 who had suffered an incident myocardial infarcti...

Thrombotic risk is associated with the estrogen dose and type of progestin in combined oral contraceptives. Studies published since 1990 showed that third-generation progestins have larger risk to contribute to thrombosis development than the second-generation. However, there are conflicts in the literature regarding the thrombotic risk associated to the drospirenone progestin. So, this study a...