Objective(s): Non- Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL) are two main hematological malignances which have been driven from lymphoid tissue. Genetic polymorphisms in tumor necrosis factor-α (TNF-α) -308 and lymphotoxin-α (LT-α) +252 may affect their transcription and expression which leads to their high plasma level. The frequency of the TNF-α (-308) and LT-...

The genetic structure of the genus Alburnus is not well known and the phylogenetic relationships among its species are uncertain. In the present study, simple sequence repeats (SSRs or microsatellites) were used to evaluate genetic diversity and genetic differentiation between Alburnus mossulensis Heckel, 1843 from Kashgan River in Lorestan province and Alburnus caeruleus Heckel, 1843 from Gama...

the genetic structure of the genus alburnus is not well known and the phylogenetic relationships among its species are uncertain. in the present study, simple sequence repeats (ssrs or microsatellites) were used to evaluate genetic diversity and genetic differentiation between alburnus mossulensis heckel, 1843 from kashgan river in lorestan province and alburnus caeruleus heckel, 1843 from gama...

Abstract The results of the study showed two genetic polymorphisms BM4505 marker for studied samples: 270/260, 280/271 bp, their distribution ratio was 60.34 and 39.66 %, respectively, which highly significant differences (P≤0.01) among polymorphisms. that there were (P≤0.05) between 270/260,280/271 bp by California mastitis test, cows carrying 270/260 where test value 1.20 on 2.47, as other tr...

inflammatory bowel disease (ibd) is a chronic disease of unknown etiology, in which genetic factors, seem to play an important role in the disease predisposition and course. assessment of tumor necrosis factor (tnf-α) gene polymorphisms in many populations showed a possible association with ibd. considering the genetic variety in different ethnic groups, the aim of the present study was to inve...

today multinational studies using genome-wide association scan (gwas) for >1000,000 polymorphisms on >100,000 cases with major psychiatric diseases versus controls, combined with next-generation sequencing have found ~100 genetic polymorphisms associated with schizophrenia (scz), bipolar disorder (bd), autism, attention deficit and hyperactivity disorder (adhd), etc. however, the effect size of...

Increasing alcohol consumption by women of childbearing age contributes to more frequent cases fetal spectrum disorder. The cause the syndrome is exposure, particularly what referred as high prenatal exposure. Low metabolic activity enzymes shifts burden ethanol removal maternal metabolism. One factors influencing pathogenesis FASD genetic background. It can determine rate elimination ethanol, ...