نتایج جستجو برای: genomic instability
تعداد نتایج: 199899 فیلتر نتایج به سال:
Genomic instability is a hallmark of breast and other solid cancers. Presumably caused by critical telomere reduction, GI is responsible for providing the genetic diversity required in the multi-step progression of the disease. We have used multicolor fluorescence in situ hybridization and 3D image analysis to quantify genomic instability cell-by-cell in thick, intact tissue sections of normal ...
Cancer-specific genomic instability in bronchial lavage: a molecular tool for lung cancer detection.
We examined genomic instability in DNA from 80 bronchial lavage samples from patients with lung cancer and individuals with no malignant lung disease. We used a multiplex assay of eight fluorescent-tagged microsatellite markers that have a very high incidence of allelic imbalance in lung tumors. When genomic instability at individual loci was analyzed statistically against diagnosis, markers D3...
1 The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, 2 Institute of Medical Engineering and Science, Department of Biological Engineering, and Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, 3 Department of Biomedical Engineering and Center of Synthetic Biology, Boston University, Bosto...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید