The present study was designed to explore the association between the SNP +405G>C of the VEGF gene with the risk of endometriosis, and endometriosis associated with adenomyosis and chocolate cysts. Following extraction of genomic DNA, genotyping of the +405 G>C polymorphisms of the VEGF gene was performed by PCR - RFLP analysis. The genotype (X2 =21.713, 2 df, P = < 0.0001) and allele (X2 =10.6...

We examined the association between the adiponectin receptor 2 gene and the risk of ischemic stroke. Polymerase chain reaction-restriction fragment length polymorphism was used to detect rs12342 genotypes of the adiponectin receptor 2 gene in 300 ischemic stroke patients and 320 age- and gender-matched healthy controls. In the patient group, the AA, GA, and GG genotype frequencies were 39.3, 42...

CYP2E1 PstI polymorphism G-1259C (rs3813867) genotype distributions vary significantly among different populations and are associated with both diseases, like cancer, and adverse drug effects. To date, there have been limited genotype distributions and allele frequencies of this polymorphism reported in the three major indigenous ethnic groups (KadazanDusun, Bajau, and Rungus) in Sabah, also kn...

OBJECTIVE To analyze a recently published meta-analysis of six studies on 5-HTTLPR polymorphism and lifelong premature ejaculation (PE). METHODS Calculation of fraction observed and expected genotype frequencies and Hardy Weinberg equilibrium (HWE) of cases and controls. LL,SL and SS genotype frequencies of patients were subtracted from genotype frequencies of an ideal population (LL25%, SL50...

The avianuncoupling protein (avUCP) is a member of the mitochondrial transporter superfamily that uncouples proton entry in the mitochondrial matrix from ATP synthesis. The polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method was used to estimate the allele and genotype frequencies of the UCP/HhaI polymorphisms and to determine associations between these polymorp...

results genotype frequencies of g/a in fertile and infertile men were significantly different (χ2 = 4.16, df = 1, p = 0.041). genotype frequencies of g/g and a/ain fertile and infertile men were not significantly different (χ2 = 3.32, df = 1, p = 0.068 and χ2 = 0.521, df = 1, p = 0.47, respectively). the risk of infertility was 1.43 folds higher in individuals with the a/a genotype compared to ...