This case was an old woman who had been suffering from peripancreatic space occupying lesions for more than 3 years. She underwent distal pancreatectomy and splenectomy. Under a microscopic examination, the tumor was composed of well-differentiated mucinous cystic neoplasm (MCN) and poorly differentiated anaplastic giant-cell carcinoma. Tumor giant-cells engulfing the neutrophils were visible i...

Resently, we treated a 69-year-old patient with squamous cell carcinoma of lung with osteoclast-like giant cells which were similar with the giant cell tumor of bone. The clinical and pathological characteristics of this case were presented, and the literatures were reviewed. The tumor differed histologically from the pleomorphic carcinoma, which occurs most commonly in the lung and showed dive...

BCC: basal cell carcinoma INTRODUCTION Basal cell carcinoma (BCC) is the most common skin cancer in the world, with 750,000 cases reported annually in the United States alone. Because they are typically identified early, it is rare to see BCCs grow beyond 5 cm in diameter; when this does occur, the term giant basal cell carcinoma applies. Furthermore, if beyond 20 cm in diameter, the lesion is ...

Combined large cell neuroendocrine carcinoma of the lungs (combined LCNEC) with giant cell carcinoma is extremely rare. A 65-year-old man was found to have an abnormal shadow in his left lung field. Computed tomography revealed a solid, round mass measuring 2.8 × 2.2 cm that was located in the left S9. The patient underwent left lower lobectomy and mediastinal lymph node dissection. Histopathol...

background: giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. giant cell tumor (gct) of the sphenoid bone is relatively rare. in this report, we describe a tumor of the greater wing of left sphenoid bone. case presentation: a 31-year-old female was presented with headache, proptosis and diplopia of her left eye. cranial magnetic resonance ima...

BACKGROUND Spontaneous regression of small basal cell carcinoma has been reported. For giant basal cell carcinoma, however, no spontaneous regression has been described to date. CASE REPORT We present a patient with two independent giant basal cell carcinomas over the left clavicle and the lower back, measuring 7 x 12 cm and 18 x 20 cm, respectively. Both tumors were excised incompletely (R2)...

A 70 year old female underwent a hysterectomy due to a diagnosis of high grade endometrioid adenocarcinoma. Pathological examination revealed a Malignant Mixed Mullerian Tumor (MMMT) along with a conventional endometrioid adenocarcinoma with a component of giant cell carcinoma. Giant cell carcinoma of the endometrium is a rare tumor consisting of sheets of discohesive appearing cells with numer...

BACKGROUND Basal cell carcinoma (BCC) greater than 5 cm in diameter is called giant basal cell carcinoma (GBCC), or super giant basal cell carcinoma if it has a diameter larger than 20 cm. Giant BCC only accounts for 0.5% of BCCs and super giant BCC is exceedingly rare. On account of their rarity, there are no established guidelines for GBCC treatment. CASE REPORT We describe a peculiar case of...

Giant cell arteritis is a granulomatous vasculitis of large and medium sized arteries manifesting as temporal arteritis and/or polymyalgia rheumatica. The histological assessment of temporal artery biopsies is frequently encountered in anatomical pathology and has important diagnostic consequences in patients clinically suspected of having giant cell arteritis. We present an intriguing case of ...

skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...