We present two cases of central giant cell granuloma in the temporal bone. CT showed an enhancing tumor causing a smoothly margined temporal squamosa and floor of the middle fossa. External carotid angiograms showed tumor stain mainly supplied by the temporal branches of the internal maxillary artery. In one case, MR images showed a hypointense mass on both T1- and T2-weighted images that was t...

Central giant cell granulomas are non-neoplastic lesions of unknown etiology. They affect females more than males with the mandibular anterior region being the most common site of occurrence. Clinically central giant cell granulomas present as asymptomatic, expansile swellings causing deviation of associated teeth. Radiologically they usually presents as multilocular lesions causing expansion o...

Giant cell reparative granulomas (GCRG) are non-neoplastic rapidly expanding and locally destructive lesions typical of facial skeleton bones. Jaffé first described these lesions in 1953, designating benign lesions of the jaw that were histologically different from true giant cell tumors of long bones. Mandibular GCRG area rare lesions, comprising less than 7% of all benign bone lesions of the ...

Discussion Giant cell reparative granuloma is an uncommon lesion that is a reactive process and not a neoplasm. At histologic analysis, giant cell reparative granulomas demonstrate plump, bland fibroblasts and multinucleated giant cells surrounding foci of hemorrhage; osteoid production along hemorrhagic foci is commonly seen. The histologic appearance of GCRG is similar to that of brown tumor ...

A case of a rare giant cell lesion of a tarsal bone, giant cell reparative granuloma, is presented with CT correlation. CT is useful in pre-operative management both in defining the extent of involvement of adjacent structures and demonstrating soft tissue abnormality.

Peripheral giant cell reparative granuloma is a reactive and rare lesion of oral cavity with unknown etiology which is derived from periosteum and periodontal ligament and occurs frequently in young adults. Inflammation or trauma is underlying causative factor of reactive proliferation. In the present case report, a 35 year-old male with aggressive periodontitis and peripheral giant cell repara...

Giant-cell reparative granuloma (GCRG) occurs in the jaw, temporal bone, and short tubular bones of the hands and feet. Although GCRG can affect long bones, only small numbers of such cases have been sporadically reported. This report describes a giant-cell reparative granuloma in the proximal tibia in a 60-year-old woman, describes features of GCRG in long bones and reviews the literature. A 6...

background and aims. the correlation between morphology of giant cells in peripheral granulomas of the jaws and the aggressive behavior of the lesion is unknown. this study investigated the correlation between the histopathologic features with demographic, gross and radiographic findings in giant cell granulomas. materials and methods. in this analytical study, data from 23 cases of central gia...

SUMMARY We present an unusual case of a giant cell reparative granuloma arising from the left temporal lobe area of a 38-year-old man and provide clinical and MR findings. Current diagnosis and treatment options are also discussed.

AIM To understand the aggressiveness of lesions in immunocompromised patients. Central giant cell granuloma (CGCG) is a non-neoplastic intraosseous lesion, anterior to the molars and more commonly in the mandible. It is an uncommon lesion accounting for less than 7% of all benign jaw lesions found predominantly in children and young adults with a female predilection of about 2:1 ratio. CASE D...